Kidney cancer in the Middle East and North Africa region: a 30-year analysis (1990-2019).

Autor: Safiri S; Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. saeidsafiri@gmail.com.; Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. saeidsafiri@gmail.com., Hassanzadeh K; Department of Urology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran., Ghaffari Jolfayi A; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mousavi SE; Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Motlagh Asghari K; Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran., Nejadghaderi SA; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.; Systematic Review and Meta-Analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Naghdi-Sedeh N; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran., Noori M; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran., Sullman MJM; Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.; Department of Social Sciences, University of Nicosia, Nicosia, Cyprus., Collins GS; Centre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Kolahi AA; Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. a.kolahi@sbmu.ac.ir.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Jun 14; Vol. 14 (1), pp. 13710. Date of Electronic Publication: 2024 Jun 14.
DOI: 10.1038/s41598-024-64521-7
Abstrakt: Kidney cancer, a type of urogenital cancer, imposes a high burden on patients. Despite this, no recent research has evaluated the burden of this type of cancer in the Middle East and North Africa (MENA) region. This study explored the burden of kidney cancer from 1990 to 2019 according to age, sex and socio-demographic index (SDI). The Global Burden of Disease (GBD) 2019 data was utilized to estimate the incidence, death, and disability-adjusted life-years (DALYs) caused by kidney cancer. These estimates were reported as counts and as age-standardised rates with 95% uncertainty intervals (UIs). The estimated age-standardised incidence, mortality, and DALY rates of kidney cancer in 2019 were 3.2 (2.8-3.6), 1.4 (1.2-1.6), and 37.2 (32.0-42.6) per 100,000, respectively. Over the period from 1990 to 2019, these rates have increased by 98.0%, 48.9%, and 37.7%, respectively. In 2019, the United Arab Emirates, Qatar, and Lebanon had the largest age-standardised incidence, mortality, and DALY rates. The smallest age-standardised incidence rates were seen in Yemen, Afghanistan, and the Syrian Arab Republic. Additionally, the smallest age-standardised mortality and DALY rates were observed in the Syrian Arab Republic, Yemen, and Morocco. The highest incidence rates were found among individuals aged 75-79 in both males and females. In 2019, the MENA/Global DALY ratio exceeded one for females aged 5-19 age and males aged 5-14, compared to 1990age groups in males. The burden of kidney cancer consistently rose with increasing SDI levels from 1990 to 2019. The increasing burden of kidney cancer highlights the urgent need for interventions aimed at improving early diagnosis and treatment in the region.
(© 2024. The Author(s).)
Databáze: MEDLINE
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