Coxsackievirus A24 causing acute conjunctivitis in a 2023 outbreak in Vietnam.

Autor:	Tran H; Hai Yen Vision Institute, Ho Chi Minh City, Vietnam., Ha T; Hai Yen Vision Institute, Ho Chi Minh City, Vietnam., Hoang L; Hai Yen Vision Institute, Ho Chi Minh City, Vietnam., Tran Y; Hai Yen Vision Institute, Ho Chi Minh City, Vietnam., Ruder K; Francis I. Proctor Foundation, University of California, San Francisco, USA., Zhong L; Francis I. Proctor Foundation, University of California, San Francisco, USA., Chen C; Francis I. Proctor Foundation, University of California, San Francisco, USA., Liu Y; Francis I. Proctor Foundation, University of California, San Francisco, USA., Yu D; Francis I. Proctor Foundation, University of California, San Francisco, USA., Abraham T; Francis I. Proctor Foundation, University of California, San Francisco, USA., Hinterwirth A; Francis I. Proctor Foundation, University of California, San Francisco, USA., Deiner M; Department of Ophthalmology, University of California, San Francisco, USA., Porco TC; Department of Ophthalmology, University of California, San Francisco, USA., Lietman TM; Francis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA., Doan T; Francis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA. Electronic address: Thuy.Doan@ucsf.edu., Seitzman GD; Francis I. Proctor Foundation, University of California, San Francisco, USA; Department of Ophthalmology, University of California, San Francisco, USA.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 Sep; Vol. 146, pp. 107133. Date of Electronic Publication: 2024 Jun 13.
DOI:	10.1016/j.ijid.2024.107133
Abstrakt:	Objectives: To determine the associated pathogen during the 2023 conjunctivitis outbreak in Vietnam METHODS: RNA-sequencing was used to identify pathogens before and during the outbreak. Results: 24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak. Conclusions: Multiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection. Competing Interests: Declarations of competing interest The authors have no relevant financial or non-financial competing interests to report. (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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