Developmental associations between cognition and adaptive behavior in intellectual and developmental disability.

Autor: Dakopolos A; UC Davis MIND Institute and Department of Psychiatry and Behavioral Sciences, 2825 50th Street, Sacramento, CA, 95817, USA., Condy E; Hofstra University, 1000 Hempstead Tpke, Hempstead, NY, 11549, USA., Smith E; Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA., Harvey D; Division of Biostatistics, Department of Public Health Sciences, UC Davis, Medical Sciences 1C, One Shields Avenue, Davis, CA, 95616, USA., Kaat AJ; Feinberg School of Medicine, Northwestern University, 625 N. Michigan Ave Suite 2700, Chicago, IL, 60611, USA., Coleman J; Regis University, 3333 Regis Boulevard, Denver, CO, 80221, USA., Riley K; Slippery Rock University of Pennsylvania, 104 Maltby Ave, Slippery Rock, PA, 16057, USA., Berry-Kravis E; Rush University Medical Center, 600 Paulina St., Chicago, IL, 60012, USA., Hessl D; UC Davis MIND Institute and Department of Psychiatry and Behavioral Sciences, 2825 50th Street, Sacramento, CA, 95817, USA. drhessl@ucdavis.edu.
Jazyk: angličtina
Zdroj: Journal of neurodevelopmental disorders [J Neurodev Disord] 2024 Jun 13; Vol. 16 (1), pp. 31. Date of Electronic Publication: 2024 Jun 13.
DOI: 10.1186/s11689-024-09542-z
Abstrakt: Background: Intellectual and developmental disabilities (IDDs) are associated with both cognitive challenges and difficulties in conceptual, social, and practical areas of living, commonly referred to as adaptive behavior (DSM-5). Although cross-sectional associations between intelligence or cognition and adaptive behavior have been reported in IDD populations, no study to date has examined whether developmental changes in cognition contribute to or track with changes in adaptive behavior. The present study sought to examine associations of longitudinal developmental change in domains of cognition (NIH Toolbox Cognition Battery, NIHTB-CB) and adaptive behavior domains (Vineland Adaptive Behavior Scales-3; VABS-3) including Socialization, Communication, and Daily Living Skills (DLS) over a two year period in a large sample of children, adolescents and young adults with IDD.
Methods: Three groups were recruited, including those with fragile X syndrome, Down syndrome, and other/idiopathic intellectual disability. Eligible participants (n = 263) included those who were between 6 and 26 years (m age  = 15.52, sd = 5.17) at Visit 1, and who had a diagnosis of, or suspected intellectual disability (ID), including borderline ID, with a mental age of at least 3.0 years. Participants were given cognitive and adaptive behavior assessments at two time points over a two year period (m = 2.45 years, range = 1.27 to 5.56 years). In order to examine the association of developmental change between cognitive and adaptive behavior domains, bivariate latent change score (BLCS) models were fit to compare change in the three cognitive domains measured by the NIHTB-CB (Fluid Cognition, Crystallized Cognition, Total Cognition) and the three adaptive behavior domains measured by the VABS-3 (Communication, DLS, and Socialization).
Results: Over a two year period, change in cognition (both Crystallized and Total Composites) was significantly and positively associated with change in daily living skills. Also, baseline cognition level predicted growth in adaptive behavior, however baseline adaptive behavior did not predict growth in cognition in any model.
Conclusions: The present study demonstrated that developmental changes in cognition and adaptive behavior are associated in children and young adults with IDD, indicating the potential for cross-domain effects of intervention. Notably, improvements in DLS emerged as a primary area of adaptive behavior that positively related to improvements in cognition. This work provides evidence for the clinical, "real life" meaningfulness of changes in cognition detected by the NIHTB-CB in IDD, and provides empirical support for the NIHTB-CB as a fit-for-purpose performance-based outcome measure for this population.
(© 2024. The Author(s).)
Databáze: MEDLINE
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