Effectiveness of Genicular Artery Embolization for Reducing Synovitis as Assessed by Contrast-Enhanced MR Imaging in Knee Osteoarthritis: A Pilot Study.

Autor:	Dablan A; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey. Electronic address: alidablan@hotmail.com., Erdim Ç; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey., Güzelbey T; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey., Cingöz M; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey., Arslan MF; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey., Mutlu İN; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey., Kılıçkesmez Ö; Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2024 Sep; Vol. 35 (9), pp. 1313-1322.e6. Date of Electronic Publication: 2024 Jun 11.
DOI:	10.1016/j.jvir.2024.06.003
Abstrakt:	Purpose: To investigate the impact of genicular artery embolization (GAE) on synovitis in knee osteoarthritis (OA) using contrast-enhanced magnetic resonance (MR) imaging and to assess its predictive role in pain response. Materials and Methods: A single-center retrospective analysis was conducted using contrast-enhanced MR imaging on 33 patients treated with GAE for knee OA between December 2022 and March 2023. MR assessments before the procedure and at 3 months after embolization were utilized in a semiquantitative scoring system for synovitis severity and distribution analysis. Pain and function through Western Ontario and McMaster Universities Osteoarthritis Index and visual analog scale scores were also assessed. Results: Significant synovitis reduction was noted after GAE, particularly in parapatellar and periligamentous areas. Synovial contrast enhancement scores significantly decreased from 5.1 (SD ± 2.0) to 2.9 (SD ± 2.0) at 3 months (P < .001), with a moderate negative correlation between synovial enhancement scores and pain levels (P = .005). Conclusions: GAE significantly reduced synovitis in knee OA, evidenced by contrast-enhanced MR imaging. The correlation between preprocedural synovial contrast enhancement scores and pain relief after the procedure, although promising, requires careful interpretation because of the complex factors affecting pain in knee OA. (Copyright © 2024 SIR. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu