A cavity induced mode hybridization plasmonic sensor for portable detection of exosomes.
Autor: | Luo X; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China., Yan S; State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China., Chen G; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China., Wang Y; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China., Zhang X; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China; Innovative Drug Research Institute, Fujian Medical University, Fuzhou, 350108, China., Lan J; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China; Innovative Drug Research Institute, Fujian Medical University, Fuzhou, 350108, China., Chen J; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China; Innovative Drug Research Institute, Fujian Medical University, Fuzhou, 350108, China. Electronic address: cjh_huaxue@126.com., Yao X; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350108, China; Innovative Drug Research Institute, Fujian Medical University, Fuzhou, 350108, China. Electronic address: xuyao@fjmu.edu.cn. |
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Jazyk: | angličtina |
Zdroj: | Biosensors & bioelectronics [Biosens Bioelectron] 2024 Oct 01; Vol. 261, pp. 116492. Date of Electronic Publication: 2024 Jun 10. |
DOI: | 10.1016/j.bios.2024.116492 |
Abstrakt: | Exosomes have been considered as promising biomarkers for cancer diagnosis due to their abundant information from originating cells. However, sensitive and reliable detection of exosomes is still facing technically challenges due to the lack of a sensing platform with high sensitivity and reproducibility. To address the challenges, here we propose a portable surface plasmon resonance (SPR) sensing of exosomes with a three-layer Au mirror/SiO Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
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