HHV-8 Linked to Kaposi's Sarcoma and Castleman's Disease in HIV-1-infected patient: Case Report and Review of the Literature.
| Autor: | Zaghdoudi A; Department of Infectious Diseases, Clermont-Ferrand University Hospital, Clermont-Ferrand, France., Harrabi H; Department of Infectious Diseases, Hospital la Rabta, Tunis, Tunisia.; Faculty of Medicine, Université de Tunis El Manar, Tunis, Tunisia., Tiouiri Benaissa H; Department of Infectious Diseases, Hospital la Rabta, Tunis, Tunisia.; Faculty of Medicine, Université de Tunis El Manar, Tunis, Tunisia. |
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| Jazyk: | angličtina |
| Zdroj: | International journal of hematology-oncology and stem cell research [Int J Hematol Oncol Stem Cell Res] 2024 Apr 01; Vol. 18 (2), pp. 202-205. |
| DOI: | 10.18502/ijhoscr.v18i2.15378 |
| Abstrakt: | Kaposi's sarcoma (KS) and multicentric Castleman's disease (MCD) are both linked to human herpesvirus-8 (HHV-8) infection which most commonly affects people living with human immunodeficiency virus (HIV). Herein, we describe the case of a 57-year-old patient who has been admitted for fever, night sweats, weight loss, and diffuse lymphadenopathy with abdominal pain. HIV status was confirmed by a positive Western blot test. His initial CD4 cell count was equal to 270 cells/µL. A histological study of a peripheral lymph node concluded that KS is associated with MCD. These two conditions found in the same patient highlight the malignant potential of HHV-8, particularly in the case of HIV-induced immunodeficiency. Competing Interests: All authors declare that they have no conflict of interest. (Copyright © 2024 Tehran University of Medical Sciences.) |
| Databáze: | MEDLINE |
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