Relationship between high trait anxiety in 22q11.2 deletion syndrome and the difficulties in medical, welfare, and educational services.

Autor: Nakajima N; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Tanaka M; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Kanehara A; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Morishima R; The Health Care Science Institute Tokyo Japan.; Department of Neuropsychiatry, Graduate School of Medicine The University of Tokyo Tokyo Japan., Kumakura Y; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan.; Department of Mental Health, Graduate School of Medicine The University of Tokyo Tokyo Japan., Ohkouchi N; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Hamada J; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Ogawa T; Department of Child Psychiatry The University of Tokyo Hospital Tokyo Japan., Tamune H; Department of Cellular Neurobiology, Graduate School of Medicine The University of Tokyo Tokyo Japan.; World-Leading Innovative Graduate Study Program for Life Science and Technology (WINGS-LST) The University of Tokyo Tokyo Japan., Nakahara M; Graduate School of Clinical Psychology Kagoshima University Kagoshima Japan., Mori S; Department of Neuropsychiatry, Graduate School of Medicine The University of Tokyo Tokyo Japan., Ichihashi K; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan., Jinde S; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan.; Department of Neuropsychiatry, Graduate School of Medicine The University of Tokyo Tokyo Japan., Kano Y; Department of Child Psychiatry The University of Tokyo Hospital Tokyo Japan.; Department of Child Neuropsychiatry, Graduate, School of Medicine The University of Tokyo Tokyo Japan., Sakamoto I; Department of Cardiovascular Medicine Kyushu University Graduate School of Medical Sciences Fukuoka Japan., Tanaka K; Department of Psychosocial Medicine National Center for Child Health and Development Tokyo Japan., Hirata Y; Department of Pediatrics Kitasato University School of Medicine Kanagawa Japan., Ohashi H; Division of Medical Genetics Saitama Children's Medical Center Saitama Japan., Shinohara T; Department of Pediatric Cardiology and Adult Congenital Cardiology Tokyo Women's Medical University Tokyo Japan., Kasai K; Department of Neuropsychiatry The University of Tokyo Hospital Tokyo Japan.; Department of Neuropsychiatry, Graduate School of Medicine The University of Tokyo Tokyo Japan.; The International Research Center for Neurointelligence (IRCN), The University of Tokyo Institutes for Advanced Study (UTIAS) The University of Tokyo Tokyo Japan.; UTokyo Institute for Diversity and Adaptation of Human Mind (UTIDAHM) The University of Tokyo Tokyo Japan.
Jazyk: angličtina
Zdroj: PCN reports : psychiatry and clinical neurosciences [PCN Rep] 2023 Feb 13; Vol. 2 (1), pp. e80. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
DOI: 10.1002/pcn5.80
Abstrakt: Aim: The 22q11.2 deletion syndrome (22q11DS) is associated with a high prevalence of mental health comorbidities. However, not enough attention has been paid to the elevated prevalence of high trait anxiety that begins early in life and may be enduring. We sought to identify specific medical, welfare, or educational difficulties associated with high trait anxiety in 22q11DS.
Methods: A questionnaire-based survey was conducted for the parents of 22q11DS individuals ( N  = 125). First, a multiple regression analysis was conducted to confirm the hypothesis that high trait anxiety in individuals with 22q11DS would be associated with parents' psychological distress. This was based on 19 questionnaire options regarding what difficulties the parents currently face about their child's disease, characteristics, and traits. Next, we explored what challenges faced in medical, welfare, and educational services would be associated with the trait anxiety in their child.
Results: The multiple regression analysis confirmed that the high trait anxiety was significantly associated with parental psychological distress ( β  = 0.265, p  = 0.018) among the 19 clinical/personal characteristics of 22q11DS. Furthermore, this characteristic was associated with various difficulties faced in the medical care, welfare, and education services, and the parent-child relationship.
Conclusion: To our knowledge, this is the first study to clarify quantitatively how the characteristic of high anxiety level in 22q11DS individuals is related to the caregivers' perceived difficulties in medical, welfare, and educational services. These results suggest the necessity of designing service structures informed of the fact that high trait anxiety is an important clinical feature of the syndrome.
Competing Interests: The authors declare no conflict of interest.
(© 2023 The Authors. Psychiatry and Clinical Neurosciences Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology.)
Databáze: MEDLINE
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