Noninvasive Ventilation in Critically Ill Patients With Severe Acute Respiratory Infections.

Autor:	Jabri G; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Alotaibi F; Emergency Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Ahmed AM; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Jose J; Department of Bioinformatics and Biostatistics, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Alenezi FZ; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Sadat M; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Humaid FB; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Al-Hameed F; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.; King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Jeddah, Saudi Arabia., Memon J; Department of Intensive Care, King Abdulaziz Hospital, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Al-Ahsa, Saudi Arabia., Al Khatib K; Intensive Care Department, Al-Noor Specialist Hospital, Makkah, Saudi Arabia., Alsuayb AM; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., AlObaidi M; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Al Mutairi M; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Alanaizi AA; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Alghamdi F; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Arabi YM; King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia arabi@ngha.med.sa yaseenarabi@yahoo.com.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Respiratory care [Respir Care] 2024 Aug 24; Vol. 69 (9), pp. 1138-1145. Date of Electronic Publication: 2024 Aug 24.
DOI:	10.4187/respcare.11286
Abstrakt:	Background: The objective of this study was to evaluate the association between noninvasive ventilation (NIV) compared with invasive ventilation and mortality in subjects with severe acute respiratory infection. Methods: This was a retrospective multi-center study of subjects with severe acute respiratory infection treated with ventilatory support between September 2012 and June 2018. We compared the 90-d mortality of subjects managed initially with NIV (NIV group) with those managed with invasive ventilation only (invasive ventilation group), adjusting by propensity score. Results: Of 383 subjects, 189 (49%) were in the NIV group and 194 (51%) were in the invasive ventilation group. Of the subjects initially treated with NIV, 117 (62%) were eventually intubated. Crude 90-d mortality was lower in the NIV group versus the invasive ventilation group (42 [22.2%] vs 77 [39.7%]; P < .001). After propensity score adjustment, NIV was associated with lower 90-d mortality than invasive ventilation (odds ratio 0.54, 95% CI 0.38-0.76; P < .001). The association of NIV with mortality compared with invasive ventilation was not different across the studied subgroups. Conclusions: In subjects with severe acute respiratory infection and acute respiratory failure, NIV was commonly used. NIV was associated with a lower 90-d mortality. The observed high failure rate suggests the need for further research to optimize patient selection and facilitate early recognition of NIV failure. Competing Interests: The authors have disclosed no conflicts of interest. (Copyright © 2024 by Daedalus Enterprises.)
Databáze:	MEDLINE
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