Novel Approaches to the Treatment of Idiopathic Intracranial Hypertension.

Autor: Subramanian PS; Department of Ophthalmology, Neurology, and Neurosurgery, University of Colorado School of Medicine, Sue Anschutz-Rodgers University of Colorado Eye Center, Aurora, CO, USA. prem.subramanian@cuanschutz.edu.; Department of Surgery (Division of Ophthalmology), Uniformed Services University of the Health Sciences, Bethesda, MD, USA. prem.subramanian@cuanschutz.edu.; UCHealth Eye Center, 1675 Aurora Ct Mail Stop F731, 80045, Aurora, CO, USA. prem.subramanian@cuanschutz.edu.
Jazyk: angličtina
Zdroj: Current neurology and neuroscience reports [Curr Neurol Neurosci Rep] 2024 Aug; Vol. 24 (8), pp. 265-272. Date of Electronic Publication: 2024 Jun 12.
DOI: 10.1007/s11910-024-01347-w
Abstrakt: Purpose of Review: Idiopathic intracranial hypertension (IIH) typically affects women of childbearing age, is associated with recent weight gain, and can result in debilitating headache as well as papilledema that can cause vision loss. There have been advances in the medical and surgical treatment of affected patients with IIH that can improve outcomes and tolerability of therapy.
Recent Findings: Medical treatment with agents that lower intracranial pressure through pathways other than carbonic anhydrase inhibition are being developed, and medically-directed weight loss as well as bariatric surgery now may be considered as primary therapy. New surgical options including venous sinus stenting have shown efficacy even with cases of severe vision loss. Our treatment options for IIH patients are becoming more diverse, and individualized treatment decisions are now possible to address specific components of the patient's disease manifestations and to lead to IIH remission.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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