Neural respiratory drive during maximal voluntary ventilation in individuals with hypertension: A case-control study.

Autor: V S O N Cavalcante A; Faculdade de Ciências da Saúde do Trairi (FACISA), Programa de Pós-Graduação em Ciências da Reabilitação, Santa Cruz, Rio Grande do Norte, Brazil., Fonseca JD; Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Araujo Cruz HR; Faculdade de Ciências da Saúde do Trairi (FACISA), Laboratório de Motricidade e Fisiologia Humana, Santa Cruz, Rio Grande do Norte, Brazil., Nascimento VF; Faculdade de Ciências da Saúde do Trairi (FACISA), Laboratório de Motricidade e Fisiologia Humana, Santa Cruz, Rio Grande do Norte, Brazil., Santana Silva JP; Faculdade de Ciências da Saúde do Trairi (FACISA), Laboratório de Motricidade e Fisiologia Humana, Santa Cruz, Rio Grande do Norte, Brazil., Lins CA; Faculdade de Ciências da Saúde do Trairi (FACISA), Programa de Pós-Graduação em Ciências da Reabilitação, Santa Cruz, Rio Grande do Norte, Brazil., Bernardes Neto SG; Faculdade de Ciências da Saúde do Trairi (FACISA), Programa de Pós-Graduação em Ciências da Reabilitação, Santa Cruz, Rio Grande do Norte, Brazil., Lima ÍND; Faculdade de Ciências da Saúde do Trairi (FACISA), Programa de Pós-Graduação em Ciências da Reabilitação, Santa Cruz, Rio Grande do Norte, Brazil.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Jun 11; Vol. 19 (6), pp. e0305044. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0305044
Abstrakt: Neural respiratory drive (NRD) is measured using a non-invasive recording of respiratory electromyographic signal. The parasternal intercostal muscle can assess the imbalance between the load and capacity of respiratory muscles and presents a similar pattern to diaphragmatic activity. We aimed to analyze the neural respiratory drive in seventeen individuals with hypertension during quite breathing and maximal voluntary ventilation (MVV) (103.9 ± 5.89 vs. 122.6 ± 5 l/min) in comparison with seventeen healthy subjects (46.5 ± 2.5 vs. 46.4 ± 2.4 years), respectively. The study protocol was composed of quite breathing during five minutes, maximum inspiratory pressure followed by maximal ventilatory ventilation (MVV) was recorded once for 15 seconds. Anthropometric measurements were collected, weight, height, waist, hip, and calf circumferences, waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), BMI, and conicity index (CI). Differences between groups were analyzed using the unpaired t-test or Mann-Whitney test to determine the difference between groups and moments. A significance level of 5% (p<0,05) was adopted for all statistical analyses. The group of individuals with hypertension presented higher values when compared to the healthy group for neural respiratory drive (EMGpara% 17.9±1.3 vs. 13.1±0.8, p = 0.0006) and neural respiratory drive index (NRDi (AU) 320±25 vs. 205.7±15,p = 0.0004) during quiet breathing and maximal ventilatory ventilation (EMGpara% 29.3±2.7 vs. 18.3±0.8, p = 0.000, NRDi (AU) 3140±259.4 vs. 1886±73.1,p<0.0001), respectively. In conclusion, individuals with hypertension presented higher NRD during quiet breathing and maximal ventilatory ventilation when compared to healthy individuals.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 V. S. O. N. Cavalcante et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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