Association of childhood food consumption and dietary pattern with cardiometabolic risk factors and metabolomics in late adolescence: prospective evidence from 'Children of 1997' birth cohort.

Autor:	He B; School of Public Health, Li Ka Shing Faculty of Medcine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China hbaoting@hku.hk., Lam HS; Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China., Sun Y; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, US., Kwok MK; School of Public Health, Li Ka Shing Faculty of Medcine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China., Leung GM; School of Public Health, Li Ka Shing Faculty of Medcine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China., Schooling CM; School of Public Health, Li Ka Shing Faculty of Medcine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.; City University of New York, Graduate School of Public Health and Health Policy, New York, US., Au Yeung SL; School of Public Health, Li Ka Shing Faculty of Medcine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Jazyk:	angličtina
Zdroj:	Journal of epidemiology and community health [J Epidemiol Community Health] 2024 Jun 10. Date of Electronic Publication: 2024 Jun 10.
DOI:	10.1136/jech-2023-221245
Abstrakt:	Background: Healthy diet might protect against cardiometabolic diseases, but uncertainty exists about its definition and role in adolescence. Method: In a subset of Hong Kong's 'Children of 1997' birth cohort (n=2844 out of 8327), we prospectively examined sex-specific associations of food consumption and dietary pattern, proxied by the Global Diet Quality Score (GDQS) at~12.0 years, with cardiometabolic risk factors and metabolomics at~17.6 years. Result: Higher vegetable (-0.04 SD, 95% CIs: -0.09 to 0.00) and soy consumption (-0.05 SD, 95% CI: -0.09 to -0.01) were associated with lower waist-to-hip ratio. Higher fruit and vegetable consumption were associated with lower fasting glucose (p<0.05). Higher fish consumption was associated with 0.06 SD (95% CI: 0.01 to 0.10) high-density lipoprotein cholesterol and -0.07 SD (95% CI: -0.11 to -0.02) triglycerides. After correcting for multiple comparisons (p<0.001), higher fish, fruit and vegetable consumption were associated with higher fatty acid unsaturation, higher concentration and percentage of omega-3 and a lower ratio of omega-6/omega-3. At nominal significance (p<0.05), higher fish consumption was associated with lower very-low-density lipoprotein and triglycerides relevant metabolomics. Higher vegetable and fruit consumption were associated with lower glycolysis-related metabolomics. Lower sugar-sweetened beverages (SSBs) consumption was associated with lower branched-chain amino acids. Similar associations with adiposity and metabolomics biomarkers were observed for GDQS. Conclusions: Higher consumption of fruit, vegetables and fish and lower ice cream and SSBs consumption were associated with lower cardiometabolic risk in adolescents. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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