Difunctionalization Processes Enabled by Hexafluoroisopropanol.
| Autor: | Piejko M; Institut de Science et d'Ingénierie Supramoléculaires (ISIS), CNRS UMR 7006, Université de Strasbourg, 8 Allée Gaspard Monge, 67000 Strasbourg, France., Moran J; Institut de Science et d'Ingénierie Supramoléculaires (ISIS), CNRS UMR 7006, Université de Strasbourg, 8 Allée Gaspard Monge, 67000 Strasbourg, France.; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.; Institut Universitaire de France (IUF), 75005 Paris, France., Lebœuf D; Institut de Science et d'Ingénierie Supramoléculaires (ISIS), CNRS UMR 7006, Université de Strasbourg, 8 Allée Gaspard Monge, 67000 Strasbourg, France. |
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| Jazyk: | angličtina |
| Zdroj: | ACS organic & inorganic Au [ACS Org Inorg Au] 2024 Mar 04; Vol. 4 (3), pp. 287-300. Date of Electronic Publication: 2024 Mar 04 (Print Publication: 2024). |
| DOI: | 10.1021/acsorginorgau.3c00067 |
| Abstrakt: | In the past 5 years, hexafluoroisopropanol (HFIP) has been used as a unique solvent or additive to enable challenging transformations through substrate activation and stabilization of reactive intermediates. In this Review, we aim at describing difunctionalization processes which were unlocked when HFIP was involved. Specifically, we focus on cyclizations and additions to alkenes, alkynes, epoxides, and carbonyls that introduce a wide range of functional groups of interest. Competing Interests: The authors declare no competing financial interest. (© 2024 The Authors. Published by American Chemical Society.) |
| Databáze: | MEDLINE |
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