Reproducibility and air gap pockets of 3D-printed brachytherapy applicator placement in high-dose-rate skin cancer.

Autor: Poltorak M; The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland. Electronic address: michal.poltorak@cskmswia.gov.pl., Banatkiewicz P; The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland., Poltorak L; Electrochemistry@Soft Interfaces Team, Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403, Lodz, Poland., Sobolewski P; The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland; Department of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland., Zimon D; The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland; Department of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland., Szwast M; Department of Chemical and Process Engineering, Warsaw University of Technology, Warynskiego 1, 00-645, Warsaw, Poland., Walecka I; The National Institute of Medicine of the Ministry of the Interior and Administration, Woloska 137, 02-507, Warsaw, Poland; Department of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.
Jazyk: angličtina
Zdroj: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2024 Jul; Vol. 123, pp. 103401. Date of Electronic Publication: 2024 Jun 08.
DOI: 10.1016/j.ejmp.2024.103401
Abstrakt: Background and Purpose: This study aimed to investigate the reproducibility of a novel approach using 3D printed brachytherapy applicators for the treatment of skin cancer. Specifically, we aimed to assess the accuracy of applicator placement and to minimize the existence of air gap pockets between the applicator and the patient's skin.
Materials and Methods: A total of 20 patients plans diagnosed with skin cancer were enrolled in this study. All patients underwent high dose rate (HDR) brachytherapy. To ensure precise applicator placement, patient-specific 3D printed applicators were designed based on individual body and tumor topography, utilizing data obtained from computer tomography (CT) scans. All applicators were fabricated using fused deposition modeling technology.
Results: The error in applicator placement was measured and found to be less than 1.0 mm on average, with a standard deviation of 0.9 mm. Additionally, the average error in air gap pockets between the applicator and the patient's skin was 0.4 mm (standard deviation was 0.5 mm). The study demonstrated that the personalized approach of 3D printed brachytherapy applicator placement in skin cancer treatment yielded highly accurate results. The average error of less than 1.0 mm in applicator positioning and the minimal air gap pockets demonstrated the reproducibility and precision of this technique.
Conclusion: Our study establishes the reproducibility and accuracy of 3D-printed brachytherapy applicator placement in the treatment of skin cancer. This personalized treatment approach offers a highly precise method for delivering radiation therapy, minimizing the risk to adjacent healthy tissues, and enhancing overall patient outcomes.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Michal Poltorak and Lukasza Poltorak are related.
(Copyright © 2024 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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