Wideband black-blood late gadolinium enhancement imaging for improved myocardial scar assessment in patients with cardiac implantable electronic devices.

Autor: Gut P; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Cochet H; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France., Caluori G; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France., El-Hamrani D; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France., Constantin M; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France., Vlachos K; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France., Sridi S; Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France., Antiochos P; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Schwitter J; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Masi A; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Sacher F; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Cardiac Pacing and Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France., Jaïs P; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Cardiac Pacing and Electrophysiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France., Stuber M; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; CIBM Center for Biomedical Imaging, Lausanne, Switzerland., Bustin A; IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, INSERM, CRCTB, U 1045, IHU Liryc, Bordeaux, France.; Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France.; Hôpital Xavier Arnozan, Pessac, France.
Jazyk: angličtina
Zdroj: Magnetic resonance in medicine [Magn Reson Med] 2024 Nov; Vol. 92 (5), pp. 1851-1866. Date of Electronic Publication: 2024 Jun 09.
DOI: 10.1002/mrm.30162
Abstrakt: Purpose: Wideband phase-sensitive inversion recovery (PSIR) late gadolinium enhancement (LGE) enables myocardial scar imaging in implantable cardioverter defibrillators (ICD) patients, mitigating hyperintensity artifacts. To address subendocardial scar visibility challenges, a 2D breath-hold single-shot electrocardiography-triggered black-blood (BB) LGE sequence was integrated with wideband imaging, enhancing scar-blood contrast.
Methods: Wideband BB, with increased bandwidth in the inversion pulse (0.8-3.8 kHz) and T 2 preparation refocusing pulses (1.6-5.0 kHz), was compared with conventional and wideband PSIR, and conventional BB, in a phantom and sheep with and without ICD, and in six patients with cardiac devices and known myocardial injury. ICD artifact extent was quantified in the phantom and specific absorption rate (SAR) was reported for each sequence. Image contrast ratios were analyzed in both phantom and animal experiments. Expert radiologists assessed image quality, artifact severity, and scar segments in patients and sheep. Additionally, histology was performed on the sheep's heart.
Results: In the phantom, wideband BB reduced ICD artifacts by 62% compared to conventional BB while substantially improving scar-blood contrast, but with a SAR more than 24 times that of wideband PSIR. Similarly, the animal study demonstrated a considerable increase in scar-blood contrast with wideband BB, with superior scar detection compared with wideband PSIR, the latter confirmed by histology. In alignment with the animal study, wideband BB successfully eliminated severe ICD hyperintensity artifacts in all patients, surpassing wideband PSIR in image quality and scar detection.
Conclusion: Wideband BB may play a crucial role in imaging ICD patients, offering images with reduced ICD artifacts and enhanced scar detection.
(© 2024 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.)
Databáze: MEDLINE
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