Impact of early versus delayed umbilical cord clamping on term neonates' haemoglobin levels: a randomized controlled trial.

Autor:	Enyinna KP; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Eleje GU; Department of Obstetrics & Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria., Odugu BU; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Nevo CO; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Ofor IJ; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Mbachu II; Department of Obstetrics & Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria., Eze CC; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Okoh DS; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Ikwuka DC; Department of Medical Physiology, College of Medicine and Health sciences, University of Rwanda, Kigali City, Rwanda., Awkadigwe FI; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Okafor CC; Department of Psychiatry, Leicestershire Partnership NHS Trust, Leicester, United Kingdom., Malachy DE; Department of Obstetrics & Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria., Ortuanya KE; Department of Obstetrics & Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu State, Nigeria., Eze HT; Department of Internal Medicine, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria., Okoro CC; Department of Obstetrics & Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria., Okafor CG; Department of Obstetrics & Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria.
Jazyk:	angličtina
Zdroj:	The Journal of international medical research [J Int Med Res] 2024 Jun; Vol. 52 (6), pp. 3000605241255836.
DOI:	10.1177/03000605241255836
Abstrakt:	Objective: To compare the effects of early and delayed cord clamping on the haemoglobin levels of neonates delivered at term. Methods: This randomized controlled trial enrolled pregnant women during the second stage of labour. They were randomized into either the early cord clamping (ECC) group or the delayed cord clamping (DCC) group in the ratio of 1:1. Following delivery of the baby, the umbilical cords of participants in the ECC group were clamped within 30 s of delivery of the neonate while those of participants in the DCC group were clamped after 2 min from the delivery of the neonate. The primary outcome measure was the effect of ECC and DCC on the haemoglobin levels of neonates delivered at term. Results: A total of 270 pregnant women were enrolled in the study. Their baseline sociodemographic and clinical characteristics were similar in both groups. There was no significant difference in the mean haemoglobin level between ECC and DCC groups at birth. The mean haemoglobin level of the neonates at 48 h postpartum was significantly higher in the DCC group than the ECC group. Conclusion: DCC at birth was associated with a significant increase in neonatal haemoglobin levels at 48 h postpartum when compared with ECC. Trial Registration: The trial was registered at Pan African Clinical Trial Registry with approval number PACTR202206735622089. Competing Interests: Declaration of conflicting interestThe authors declare that there are no conflicts of interest.
Databáze:	MEDLINE
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