Review of imaging findings in hepatic veno-occlusive disease.

Autor: Simpson S; University of Washington School of Medicine, Seattle, WA, USA., Breshears E; Department of Radiology, University of Washington, Seattle, WA, USA., Basavalingu D; Department of Radiology, University of Washington, Seattle, WA, USA., Khatri G; Department of Radiology, University of Washington, Seattle, WA, USA., Chan S; Department of Radiology, Children's Mercy Hospital, Kansas City, MO, USA., Fite J; Department of Radiology, Children's Mercy Hospital, Kansas City, MO, USA., Swanson P; Department of Pathology, University of Washington, Seattle, WA, USA., Dighe M; Department of Radiology, University of Washington, Seattle, WA, USA. Electronic address: dighe@uw.edu.
Jazyk: angličtina
Zdroj: European journal of radiology [Eur J Radiol] 2024 Aug; Vol. 177, pp. 111526. Date of Electronic Publication: 2024 Jun 03.
DOI: 10.1016/j.ejrad.2024.111526
Abstrakt: Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is a potentially life-threatening complication of hematopoietic stem cell transplantation. Patients present with right upper-quadrant abdominal pain, jaundice, weight gain, and conjugated hyperbilirubinemia. Early diagnosis of VOD is essential to promptly initiate defibrotide therapy, which has been demonstrated to enhance survival and achieve complete resolution of disease in some patients. Historically, VOD was diagnosed by the modified Seattle or Baltimore criteria, which are both based on clinical symptoms. Alongside advancements in medical imaging over the last 40 years, the diagnosis of VOD has evolved to include the use of ultrasound, elastography, cross-sectional imaging, and image guided biopsy. Identification and interpretation of findings of VOD across imaging modalities is now a critical aspect of post-HSCT care. This review will outline the imaging findings and recommendations for the use of imaging in the management of VOD including gray-scale, color and spectral Doppler ultrasound, ultrasound elastography, CT, MRI, and liver biopsy.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Published by Elsevier B.V.)
Databáze: MEDLINE
Externí odkaz: