Multidrug resistance profile in Lactobacillus delbrueckii: a food industry species with probiotic properties.

Autor: Quaresma LS; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Santos RCV; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Gomes GC; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Américo MF; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Campos GM; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Laguna JG; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Barroso FAL; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil., Azevedo V; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil. vasco@icb.ufmg.br., de Jesus LCL; Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil. luiislimma@gmail.com.
Jazyk: angličtina
Zdroj: World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2024 Jun 08; Vol. 40 (8), pp. 235. Date of Electronic Publication: 2024 Jun 08.
DOI: 10.1007/s11274-024-04046-3
Abstrakt: Lactobacillus delbrueckii, a widely used lactic acid bacterium in the food industry, has been studied for its probiotic properties and reservoir of antibiotic-resistant genes, raising safety concerns for probiotic formulations and fermented products. This review consolidates findings from 60 articles published between 2012 and 2023, focusing on the global antibiotic resistance profile and associated genetic factors in L. delbrueckii strains. Resistance to aminoglycosides, particularly streptomycin, kanamycin, and gentamicin, as well as resistance to glycopeptides (vancomycin), fluoroquinolones (ciprofloxacin), and tetracyclines was predominant. Notably, although resistance genes have been identified, they have not been linked to mobile genetic elements, reducing the risk of dissemination. However, a significant limitation is the insufficient exploration of responsible genes or mobile elements in 80% of studies, hindering safety assessments. Additionally, most articles originated from Asian and Middle Eastern countries, with strains often isolated from fermented dairy foods. Therefore, these findings underscore the necessity for comprehensive analyses of new strains of L. delbrueckii for potential industrial and biotherapeutic applications and in combating the rise of antibiotic-resistant pathogens.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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