Acute coronary syndrome in young (≤45 years) patients: a multi-centre observational study.

Autor:	Shrateh ON; Faculty of Medicine., Al-Tawil M; Al-Azhar Faculty of Medicine, Al-Quds University., Awad A; Faculty of Medicine., Zeer ZMM; Faculty of Medicine., Owais TA; Faculty of Pharmacy, Beni-Suef University, Beni-suef, Egypt., Sinokrot A; Faculty of Medicine., Zuaiter B; Faculty of Medicine., Thraiee Y; Faculty of Medicine., Ahmed A; Faculty of Medicine., Abo Jheasha A; Faculty of Medicine., Alrojoub S; Faculty of Medicine., Hour S; Faculty of Medicine., Mtour A; Faculty of Medicine., Arda Y; Faculty of Medicine., Zuaiter K; Faculty of Medicine., Jamee A; Departement of Cardiology, Al-Shifa Hospital, Gaza., Mtour S; Department of Cardiology, Al-Makassed Hospital, Jerusalem., Nassr M; Departement of Cardiology, Al-Ahli Hospital, Hebron., Neirat S; Departement of Cardiology, Ibn Sina Hospital, Nablus, Palestine.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 May 06; Vol. 86 (6), pp. 3303-3309. Date of Electronic Publication: 2024 May 06 (Print Publication: 2024).
DOI:	10.1097/MS9.0000000000002125
Abstrakt:	Introduction: Acute coronary syndrome (ACS) in young individuals (≤45 years) is increasingly recognized as a significant health concern, yet research in this demographic remains limited, particularly within the Palestinian context. This study aims to bridge this gap by comprehensively investigating the clinical characteristics, age-specific profiles, gender disparities, treatment modalities, and angiographic patterns of ACS in young patients compared to their older counterparts. Materials and Methods: A multi-centre observational study was conducted, enroling 468 participants aged 18-55 diagnosed with ACS and admitted to three prominent Palestinian hospitals. Data were collected from medical records, and statistical analysis was performed to assess demographic characteristics, clinical presentations, risk factors, treatment strategies, and outcomes. Results: The majority of participants were male (87%), with a higher proportion in the older age group (>45 years). Clinical presentations varied, with non-ST segment elevation myocardial infarction (NSTEMI) being the most common diagnosis (48%). Risk factors such as smoking, hypertension, and diabetes were prevalent, with notable gender and age-specific differences. Percutaneous coronary intervention (PCI) was the predominant treatment strategy (83%), with consistent medication use across age groups. Conclusion: ACS in young patients poses a significant public health challenge in Palestine, necessitating tailored preventive strategies and comprehensive management approaches. Understanding the unique demographic and clinical characteristics of young ACS patients is crucial for informing targeted interventions and policies aimed at reducing the burden of cardiovascular disease in this population. These findings contribute valuable insights to the existing literature and underscore the importance of further research in this area to improve outcomes and mitigate the impact of ACS in young individuals globally. Competing Interests: All the authors had no disclosure of conflict.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu