Phytochemical profile, enzyme inhibition, antioxidant, and antibacterial activity of Rosa pimpinellifolia L.: A comprehensive study to investigate the bioactivity of different parts (whole fruit, pulp, and seed part) of the fruit.

Autor: Findik BT; Nevsehir Hacı Bektas Veli University, Faculty of Arts and Sciences, Department of Chemistry, 50300 Nevsehir, Turkiye. Electronic address: btfindik@nevsehir.edu.tr., Yildiz H; Nevsehir Hacı Bektas Veli University, Faculty of Engineering and Architecture, Department of Food Engineering, 50300 Nevsehir, Turkiye. Electronic address: hilalyildiz@nevsehir.edu.tr., Akdeniz M; The Council of Forensic Medicine, Diyarbakir Group Chairmanship, 21280 Diyarbakir, Turkiye., Yener I; Dicle University, Faculty of Pharmacy, Department of Analytical Chemistry, 21280 Diyarbakir, Turkiye. Electronic address: ismail.yener@dicle.edu.tr., Yilmaz MA; Dicle University, Faculty of Pharmacy, Department of Analytical Chemistry, 21280 Diyarbakir, Turkiye., Cakir O; Bayburt University, Faculty of Engineering, Department of Food Engineering, 69000 Bayburt, Turkiye. Electronic address: ocakir@bayburt.edu.tr., Ertas A; Dicle University, Faculty of Pharmacy, Department of Analytical Chemistry, 21280 Diyarbakir, Turkiye.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Oct 15; Vol. 455, pp. 139921. Date of Electronic Publication: 2024 May 31.
DOI: 10.1016/j.foodchem.2024.139921
Abstrakt: The pharmaceutical and nutraceutical potentials of whole fruit, pulp and seeds of Rosa pimpinellifolia L. were evaluated. Forty-two phenolic compounds and two triterpenoids were identified in extracts by LC-MS/MS and GC-MS, respectively. The most prominent compounds were ellagic acid, catechin, epicatechin, tannic acid, quercetin, oleanolic acid, and ursolic acid. The highest enzyme inhibitory activities of the extracts (94.83%) were obtained against angiotensin-converting enzyme and were almost equal to those of the commercial standard (lisinopril, 98.99%). Whole fruit and pulp extracts (IC 50 :2.47 and 1.52 μg DW/mL) exhibited higher antioxidant capacity than the standards (α-tocopherol, IC 50 :9.89 μg DW/mL). The highest antibacterial activity was obtained against Bacillus cereus (MIC: 256 μg/mL) for the whole fruit extract. Correlation analyses were conducted to find the correlation between individual phenolics and enzyme inhibitory activities. The results showed the remarkable future of not only the edible part but also the seeds of black rose hips in phytochemical and functional aspects.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023. Published by Elsevier Ltd.)
Databáze: MEDLINE
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