Cardiovascular Risk Factors and Echocardiographic Findings in a Predominantly Black Population with Rheumatoid Arthritis and Heart Failure.

Autor:	Hasan A; Department of Rheumatology, UCSF at Fresno, Fresno, CA 93701., Zaidi SM; Department of Cardiology, UCSF at Fresno, Fresno, CA 93701., Zaveri S; Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Taklalsingh N; Department of Cardiology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Zonnoor SL; Department of Rheumatology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Casillas-Gonzalez J; Department of Cardiology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Chandrakumar H; Department of Cardiology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Tadayoni A; Department of Cardiology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Sharif S; Department of Rheumatology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Connelly C; Department of Pathology, NYP Hospital-Columbia University Medical Center, New York, NY 10032., Soleiman A; Department of Medicine, Montefiore Medical Center: Einstein Campus, Bronx, NY 10467., Sezhian T; Department of Medicine, Montefiore Medical Center: Einstein Campus, Bronx, NY 10467., Sreedhara K; Division of Hospital Medicine, University of Pennsylvania, Philadelphia, PA 19104., Tsui CL; Department of Medicine, NYU Grossman New York, NY 10022., Prysyazhnyuk Y; Department of Medicine, Zucker Northwell NS/LIJ - NY Hempstead, NY 11549., Gruenstein D; Department of Dermatology, SUNY Downstate, Brooklyn, NY 11203., Melamed A; Department of Anesthesiology, Rutgers Robert Wood Johnson Medical Center, New Brunswick, NJ 08901., Oleszak F; Division of Cardiology, Sanford School of Medicine University of South Dakota, Sioux Falls, SD 57107., Axman R; Department of Medicine, New York-Presbyterian/Weill Cornell Medical Center, New York, NY 10065., Beltre D; Department of Surgery, Brown University, Providence, RI 02903., Kazi A; Department of Medicine, University of Rochester/Strong Memorial, Rochester, NY 14642., Patwari F; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 11025., Tsai A; Department of Medicine, Zucker Northwell NS/LIJ - NY Hempstead, NY 11549., Freilich M; Department of Medicine, Montefiore Medical Center: Einstein Campus, Bronx, NY 10467., Corominas A; Department of Rheumatology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., Koci K; Department of Rheumatology, Icahn School of Medicine at Mount Sinai Morningside/Mount Sinai West, New York, New York, NY 10025., Siddique O; Department of Internal Medicine, NYC H+H/South Brooklyn Health, Brooklyn, NY 11235., Marder R; Department of Orthopedic Surgery, St. Joseph's University Medical Center Paterson NJ 07503., Kirou R; Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY 11203., McFarlane IM; Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY 11203.
Jazyk:	angličtina
Zdroj:	Critical pathways in cardiology [Crit Pathw Cardiol] 2024 Jun 06. Date of Electronic Publication: 2024 Jun 06.
DOI:	10.1097/HPC.0000000000000365
Abstrakt:	Among White rheumatoid arthritis (RA) cohorts, heart failure with preserved ejection fraction (HFpEF) is the most prevalent type of heart failure (HF). We aimed to assess the type of HF affecting Black RA patients. 64 patients with RA-HF were compared to age-, sex-, and race-matched RA patients without HF. Left ventricular ejection fraction (LVEF), wall motion abnormalities, left ventricle (LV) mass, and wall thickness were reviewed. 87.3% were Black, 84.4% were women, with a mean age of 69.6 ± 1.38 (± SEM) and BMI (kg/m 2) 29.6 ± 1.07. RA-HF patients had higher rates of hypertension (HTN), chronic kidney disease, and atrial fibrillation. 66.7% had ≥3 cardiovascular risk factors compared to RA patients without HF. 2D-echocardiograms of RA-HF revealed that 62.3% had LVEF ≥50%, 37% had diastolic dysfunction, and 43.1% had wall motion abnormalities. LV mass and relative wall thickness measurements indicated LV eccentric remodeling. The odds ratio for HF was 4.7 (1.5-14.53 CI), p<0.01, among RA-HTN group and 3.5 (1.091-11.7 CI) p<0.01 among smokers. In our predominantly Black RA-HF patients, HFpEF was the most common type of HF. HTN was associated with the highest OR for HF. Eccentric hypertrophic remodeling, a known poor prognostic indicator for cardiovascular events, was found. Further studies are required to confirm our findings. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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