Antimicrobial susceptibility of Pasteurella multocida strains isolated from different host species.

Autor: Pintér K; 1HUN-REN Veterinary Medical Research Institute, Budapest, Hungary., Pollák BD; 1HUN-REN Veterinary Medical Research Institute, Budapest, Hungary., Gantelet H; 2Ceva Biovac, Beaucouzé, France., Magyar T; 1HUN-REN Veterinary Medical Research Institute, Budapest, Hungary.
Jazyk: angličtina
Zdroj: Acta veterinaria Hungarica [Acta Vet Hung] 2024 Jun 05; Vol. 72 (2), pp. 71-79. Date of Electronic Publication: 2024 Jun 05 (Print Publication: 2024).
DOI: 10.1556/004.2024.01051
Abstrakt: The spread of antibiotic resistance is one of the biggest challenges of our time, making it difficult to treat bacterial diseases. Pasteurella multocida is a widespread facultative pathogenic bacterium, which causes a wide range of diseases in both mammals and birds. In the present study, antibiotic susceptibility of 155 P. multocida strains were tested using the broth microdilution method to obtain the minimum inhibitory concentration (MIC) values for 15 antibiotics. The most effective antibiotics against pasteurellosis were ceftiofur, tetracycline, doxycycline, florfenicol and tilmicosin. Of the strains, 12 proved to be multi-drug resistant (MDR). To combat antibiotic resistance, it is important to establish a pre-treatment antibiotic susceptibility profile. A well-chosen antibiotic would not only make the treatment more successful but may also slow down the spread of resistance and the evolution of MDR strains.
Databáze: MEDLINE