Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy.

Autor: McCabe SM; Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. karen.faulds@strath.ac.uk.; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK.; The Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, SP4 0JQ, UK., Gardiner H; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK., Mullen C; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK., Wallace GQ; Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. karen.faulds@strath.ac.uk., Shand NC; The Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, SP4 0JQ, UK., Mullen AB; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK., Horan L; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK., Graham D; Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. karen.faulds@strath.ac.uk., Faulds K; Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. karen.faulds@strath.ac.uk., Boyd M; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK.
Jazyk: angličtina
Zdroj: The Analyst [Analyst] 2024 Jun 24; Vol. 149 (13), pp. 3513-3517. Date of Electronic Publication: 2024 Jun 24.
DOI: 10.1039/d4an00617h
Abstrakt: Live chicken egg embryos offer new opportunities for evaluation and continuous monitoring of tumour growth for in vivo studies compared to traditional rodent models. Here, we report the first use of surface enhanced Raman scattering (SERS) mapping and surface enhanced spatially offset Raman scattering (SESORS) for the detection and localisation of targeted gold nanoparticles in live chicken egg embryos bearing a glioblastoma tumour.
Databáze: MEDLINE