Non-invasive efficacy assessment of pulsed dye laser and photodynamic therapy for port-wine stain.

Autor: Tian R; Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China., Wang Q; Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China., Li S; Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China., Nong X; Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
Jazyk: angličtina
Zdroj: Indian journal of dermatology, venereology and leprology [Indian J Dermatol Venereol Leprol] 2024 Sep-Oct; Vol. 90 (5), pp. 615-622.
DOI: 10.25259/IJDVL_985_2023
Abstrakt: Port wine stain (PWS) is a congenital vascular malformation that commonly occurs on the face and neck. Currently, the main treatments for port wine stain are pulsed dye laser (PDL) and photodynamic therapy (PDT). However, the efficacy evaluation of PWS mostly relies on the subjective judgement of clinicians, and it is difficult to accurately respond to many small changes after treatment. Therefore, some non-invasive and efficient efficacy assessment methods are also needed. With the continuous development of technology, there are currently many visualisation instruments to evaluate PWS, including dermoscopy, VISIA-CR™ system, reflectance confocal microscopy (RCM), high-frequency ultrasound (HFUS), optical coherence tomography (OCT), Photoacoustic imaging (PAI), laser speckle imaging (LSI) and laser Doppler imaging (LDI). Among them, there are simple and low-cost technologies such as dermoscopy and the VISIA-CR™ system, but they may not be able to observe the deeper structures of PWS. At this time, combining techniques such as HFUS and OCT to increase penetration depth is crucial to evaluate PWS. In the future, the combination of these different technologies could help overcome the limitations of a single technology. This article provides a systematic overview of non-invasive methods for evaluating treatment efficacy in port wine stains and summarises their advantages and disadvantages.
Databáze: MEDLINE
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