Esophageal schwannoma mimicking non-functional parathyroid adenoma on 99m Tc-sestamibi imaging: a case report.

Autor:	Fiore R; Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Gombert E; Service of Otolaryngology and Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., La Rosa S; Institute of Pathology, Department of Laboratory Medicine and Pathology, University of Lausanne, Lausanne, Switzerland.; Service of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy., Dunet V; Service of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Sykiotis GP; Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Gorostidi F; Service of Otolaryngology and Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Jazyk:	angličtina
Zdroj:	Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 May 22; Vol. 15, pp. 1258233. Date of Electronic Publication: 2024 May 22 (Print Publication: 2024).
DOI:	10.3389/fendo.2024.1258233
Abstrakt:	Technetium-99m sestamibi single-photon emission computed tomography/computed tomography ( 99m Tc-sestamibi SPECT/CT) is a mainstay of the pre-operative localization of parathyroid lesions. We report here the case of a 30 year-old woman with a fortuitously discovered 2 cm cervical mass for which a parathyroid origin was originally suspected due to its retro-thyroidal localization and a personal history of nephrolithiasis. Normal serum calcium and parathyroid hormone (PTH) levels excluded primary hyperparathyroidism, raising suspicion of a non-functional parathyroid adenoma, and SPECT/CT imaging showed that the mass was 99m Tc-sestamibi-avid. Fine-needle aspiration (FNA) was performed; cytology was non-diagnostic but the needle washout was negative for thyroglobulin, calcitonin and PTH, arguing against a thyroidal or parathyroidal origin of the mass. Core needle biopsy revealed a schwannoma, ostensibly originating from the recurrent laryngeal nerve; upon surgical resection, it was finally found to arise from the esophageal submucosa. This case illustrates the fact that endocrinologists, radiologists, nuclear medicine, head and neck, and other specialists investigating patients with cervical masses should be aware that schwannomas need to be considered in the differential diagnosis of focal 99m Tc-sestamibi uptake in the neck region. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Fiore, Gombert, La Rosa, Dunet, Sykiotis and Gorostidi.)
Databáze:	MEDLINE
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