[About a case of primary laryngeal mucosal melanoma in a patient with medical history of oropharyngeal squamous carcinoma].

Autor: Michaut A; Service d'anatomie pathologique, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France., Clair G; Service d'anatomie pathologique, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France., Hanau E; Service d'anatomie pathologique, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France., Ratour J; Service d'anatomie pathologique, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France., Laccoureye O; Service d'oto-rhino-laryngologie, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France., Badoual C; Service d'anatomie pathologique, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France. Electronic address: cecile.badoual@egp.aphp.fr.
Jazyk: francouzština
Zdroj: Annales de pathologie [Ann Pathol] 2024 Jun 04. Date of Electronic Publication: 2024 Jun 04.
DOI: 10.1016/j.annpat.2024.04.017
Abstrakt: Introduction: Primary laryngeal mucosal melanoma is a rare tumour with a poor prognosis. Its often difficult diagnosis should rule out laryngeal metastatic localization of cutaneous melanoma.
Case Presentation: We report a case of primary laryngeal mucosal melanoma diagnosed in a 65-year-old man, treated 6 years previously with radio-chemotherapy and surgery for squamous cell carcinoma of the right lateral oropharyngeal region. The definitive diagnosis of primary laryngeal mucosal melanoma was made on the resection specimen, whereas the initial biopsy of the epilaryngeal mass discovered during the patient's surveillance had concluded that it was a laryngeal recurrence of the known squamous cell carcinoma.
Discussion: Through this case, we propose to remind the main characteristics and the diagnostic pitfalls of these tumours.
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Databáze: MEDLINE