A new method based on dispersive solid phase microextraction with commercial MOFs coupled to LC-MS/MS for the determination of isoflavones in soy drinks.

Autor: Bustamante-Rangel M; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain. Electronic address: mbr@usal.es., Del Nogal Sánchez M; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain., García-García S; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain., Conejo-Valverde P; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain., Rodríguez-Gonzalo E; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain., Pavón JLP; Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemical Sciences, Plaza Caídos s/n, University of Salamanca, Salamanca 37008, Spain.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Oct 15; Vol. 455, pp. 139861. Date of Electronic Publication: 2024 May 29.
DOI: 10.1016/j.foodchem.2024.139861
Abstrakt: For the first time, a method based on dispersive solid phase microextraction (D-μSPE) using commercial metal-organic frameworks coupled to liquid chromatography-triple quadrupole tandem mass spectrometry (LC-MS/MS) has been proposed for the determination of isoflavones in soy drinks. The use of commercial sorbents simplifies the sample treatment procedure and allows their application to routine analysis. Optimization of the parameters involved in the microextraction process was carried out using a Box-Behnken experimental design. Under the optimized conditions, the limits of detection ranged between 2 and 7 μg L -1 ; the intra-day and inter-day precision were <10 and 20%, respectively, and the recoveries were in the range of 61-120%. No significant matrix effect was found, which allowed the use of external standard calibration method. The method was successfully applied to the determination of isoflavones in commercial soy milk samples.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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