Circadian markers as a predictor of response in the treatment of depression-A systematic review.

Autor: Druiven SJM; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands. Electronic address: s.j.m.druiven@umcg.nl., Hovenkamp-Hermelink JHM; Department of Practice-Oriented Scientific Research (PWO), Alliade Care Group, Heerenveen, the Netherlands., Kamphuis J; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands., Haarman BCM; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands., Meesters Y; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands., Riese H; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands., Schoevers RA; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, the Netherlands.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2024 Aug; Vol. 338, pp. 115976. Date of Electronic Publication: 2024 May 23.
DOI: 10.1016/j.psychres.2024.115976
Abstrakt: Despite many available treatment options for depression, response rates remain suboptimal. To improve outcome, circadian markers may be suitable as markers of treatment response. This systematic review provides an overview of circadian markers that have been studied as predictors of response in treatment of depression. A search was performed (EMBASE, PUBMED, PSYCHINFO) for research studies or articles, randomized controlled trials and case report/series with no time boundaries on March 2, 2024 (PROSPERO: CRD42021252333). Other criteria were; an antidepressant treatment as intervention, treatment response measured by depression symptom severity and/or occurrence of a clinical diagnosis of depression and assessment of a circadian marker at baseline. 44 articles, encompassing 8,772 participants were included in the analysis. Although additional research is needed with less variation in types of markers and treatments to provide definitive recommendations, circadian markers, especially diurnal mood variation and chronotype, show potential to implement as response markers in the clinic.
Competing Interests: Declaration of competing interest SJMD, JHMHH, JK, BCMH, YM, HR and RAS declare no competing interests.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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