The macroeconomic impact of a dengue outbreak: Case studies from Thailand and Brazil.

Autor: Marczell K; Evidera, Budapest, Hungary., García E; Takeda International AG, Zürich, Switzerland., Roiz J; Evidera, London, United Kingdom., Sachdev R; Evidera, Bethesda, Maryland, United States of America., Towle P; Takeda Pharmaceuticals International AG, Singapore., Shen J; Takeda International AG, Zürich, Switzerland., Sruamsiri R; Takeda Thailand Ltd, Bangkok, Thailand., da Silva BM; Takeda Pharmaceuticals Brazil, São Paulo, Brazil., Hanley R; Takeda International AG, Zürich, Switzerland.
Jazyk: angličtina
Zdroj: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jun 03; Vol. 18 (6), pp. e0012201. Date of Electronic Publication: 2024 Jun 03 (Print Publication: 2024).
DOI: 10.1371/journal.pntd.0012201
Abstrakt: Background: Dengue is spreading in (sub)tropical areas, and half of the global population is at risk. The macroeconomic impact of dengue extends beyond healthcare costs. This study evaluated the impact of dengue on gross domestic product (GDP) based on approaches tailored to two dengue-endemic countries, Thailand and Brazil, from the tourism and workforce perspectives, respectively.
Findings: Because the tourism industry is a critical economic sector for Thailand, lost tourism revenues were estimated to analyze the impact of a dengue outbreak. An input-output model estimated that the direct effects (on international tourism) and indirect effects (on suppliers) of dengue on tourism reduced overall GDP by 1.43 billion US dollars (USD) (0.26%) in the outbreak year 2019. The induced effect (reduced employee income/spending) reduced Thailand's GDP by 375 million USD (0.07%). Overall, lost tourism revenues reduced Thailand's GDP by an estimated 1.81 billion USD (0.33%) in 2019 (3% of annual tourism revenue). An inoperability input-output model was used to analyze the effect of workforce absenteeism on GDP due to a dengue outbreak in Brazil. This model calculates the number of lost workdays associated with ambulatory and hospitalized dengue. Input was collected from state-level epidemiological and economic data for 2019. An estimated 22.4 million workdays were lost in the employed population; 39% associated with the informal sector. Lost workdays due to dengue reduced Brazil's GDP by 876 million USD (0.05%).
Conclusions: The economic costs of dengue outbreaks far surpass the direct medical costs. Dengue reduces overall GDP and inflicts national economic losses. With a high proportion of the population lacking formal employment in both countries and low income being a barrier to seeking care, dengue also poses an equity challenge. A combination of public health measures, like vector control and vaccination, against dengue is recommended to mitigate the broader economic impact of dengue.
Competing Interests: I have read the journal’s policy and the authors of this manuscript have the following competing interests. K.M. and R.Sa. are employees of Evidera, a part of PPD, that is a research company providing consulting and other research services to pharmaceutical, medical device, and related organizations; in their salaried positions, they work with a variety of companies and are precluded from receiving payment or honoraria directly from these organizations for services rendered. At the time the study was conducted, J.R. was also an employee of Evidera. E.G., P.T., J.S., R.Sr., B.M.S., and R.H. are employees of Takeda and may own stock/options in Takeda.
(Copyright: © 2024 Marczell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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