Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk.

Autor:	Cardona MI; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany., Luppa M; Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany., Zülke A; Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany., Kroeber ES; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Bauer A; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Döhring J; Institute of General Practice, University of Kiel, Kiel, Germany., Escales C; Institute of General Practice, University of Kiel, Kiel, Germany., Brettschneider C; Department of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Frese T; Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Kosilek RP; Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany., Gensichen J; Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany., Hoffmann W; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Kaduszkiewicz H; Institute of General Practice, University of Kiel, Kiel, Germany., König HH; Department of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wiese B; MHH Information Technology, Hannover Medical School, Hannover, Germany., Riedel-Heller SG; Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany., Thyrian JR; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Jazyk:	angličtina
Zdroj:	American journal of Alzheimer's disease and other dementias [Am J Alzheimers Dis Other Demen] 2024 Jan-Dec; Vol. 39, pp. 15333175241257849.
DOI:	10.1177/15333175241257849
Abstrakt:	While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up ( P = .674), subgroup analysis revealed improved self-efficacy ( P = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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