Intraocular lens calcification in a patient with Ehlers-Danlos syndrome.

Autor: Maguire MJ; St Thomas' Hospital, London, UK., Munro DJ; David J Apple Laboratory, Heidelberg, Germany., Merz P; David J Apple Laboratory, Heidelberg, Germany., Laidlaw A; St Thomas' Hospital, London, UK., Auffarth GU; David J Apple Laboratory, Heidelberg, Germany.
Jazyk: angličtina
Zdroj: American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2024 May 21; Vol. 35, pp. 102080. Date of Electronic Publication: 2024 May 21 (Print Publication: 2024).
DOI: 10.1016/j.ajoc.2024.102080
Abstrakt: Introduction: Calcification of hydrophilic intraocular lenses (IOL) is a rare complication following cataract surgery. Secondary calcification is described as due to host factors or changes in the IOL environment and uveitis, proliferative diabetic retinopathy and sequelae of ocular surgery are recognised potentiators. The impact of systemic connective tissue disease on IOL opacification is yet to described.
Purpose: To describe the clinical presentation and management of a young patient, with a rare subtype of Ehlers-Danlos syndrome, who presented with secondary IOL calcification 14 years after primary IOL insertion.
Observations: Floret-like lesions were observed on the IOL surface. Positive staining for calcification was observed with Alizarin red and von Kossa method on laboratory analysis.
Conclusions and Importance: Patients with systemic connective tissue disease, such as a subtype of Ehlers-Danlos, may present with secondary IOL calcification many years after primary lens insertion. This poses an additional consideration when implanting IOLs in these patients.Good visual acuity can be achieved with IOL exchange.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2024 The Authors.)
Databáze: MEDLINE