Cervical cancer: Challenges and prevention strategies: A narrative review.

Autor: Tsige AW; Department of Pharmacy, Asrat Woldeyes Health Science Campus Debre Berhan University Debre Berhan Ethiopia., Beyene DA; Department of Pharmacy, Asrat Woldeyes Health Science Campus Debre Berhan University Debre Berhan Ethiopia.
Jazyk: angličtina
Zdroj: Health science reports [Health Sci Rep] 2024 May 30; Vol. 7 (6), pp. e2149. Date of Electronic Publication: 2024 May 30 (Print Publication: 2024).
DOI: 10.1002/hsr2.2149
Abstrakt: Background and Aims: Human papillomavirus (HPV) infections that continue to exist are the main cause of cervical cancer (CC), two-thirds of CC occurrences worldwide are caused by HPV 16 and HPV 18, and 99.7% of CC tumors are linked to oncogenic HPV infection. To identify challenges of CC and its prevention and treatment modalities.
Methods: This review examined the epidemiology, predisposing factors, genetic factors, clinical assessment methods, current treatment options, and prevention approaches for CC. We had perform a narrative data synthesis rather than a pooled analysis. A thorough literature search in pertinent databases related to CC was done with the inclusion of data that were published in the English language.
Results: Early detection of CC is of utmost importance to detect precancerous lesions at an early stage. Therefore, all responsible agencies concerned with health should make all women aware of the benefits of CC screening and educate the general public. HPV vaccination coverage is very low in resource-limited settings.
Conclusion: To achieve the goal of eliminating CC as a public health problem in 2030, the World Health Organization will pay special attention to increasing HPV vaccination coverage throughout the world. To further improve HPV vaccine acceptability among parents and their children, safety-related aspects of the HPV vaccine should be further investigated through post-marketing surveillance and multicentre randomized clinical trials.
Competing Interests: The authors declare no conflict of interest.
(© 2024 The Authors. Health Science Reports published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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