Cholestasis Linked to Bodybuilding Supplements: Exploring the Risks of Contamination.

Autor: Matusak M; Department of Family Medicine, University of Wisconsin Hospital and Clinics, Madison, USA., Aljabban J; Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, USA., Wirtz M; Department of Family Medicine, University of Wisconsin Hospital and Clinics, Madison, USA., Agni R; Department of Pathology, University of Wisconsin Hospital and Clinics, Madison, USA., Spengler E; Department of Gastroenterology and Hepatology, University of Wisconsin Hospital and Clinics, Madison, USA.
Jazyk: angličtina
Zdroj: Case reports in hepatology [Case Reports Hepatol] 2024 May 24; Vol. 2024, pp. 5112461. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).
DOI: 10.1155/2024/5112461
Abstrakt: Drug-induced liver injury resulting from herbal and dietary supplement use is increasingly common and underrecognized. We report a case of a 34-year-old male recreational bodybuilder who presented with muscle cramping, fatigue, and diffuse itching in the setting of bodybuilding supplement use. Labs showed cholestatic liver injury, and liver biopsy revealed bland cholestasis and sinusoidal dilation. He was diagnosed with anabolic-androgenic steroid-induced liver injury. He was symptomatically managed with plasmapheresis for debilitating pruritus. This case highlights drug-induced liver injury as a complication of bodybuilding supplement use containing unlabeled anabolic-androgenic steroids. Sports medicine providers should inquire on herbal and dietary supplement use and be aware of potential contaminants.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2024 Mark Matusak et al.)
Databáze: MEDLINE
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