Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews.

Autor: Plans-Beriso E; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain. elena.plans@isciii.es.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain. elena.plans@isciii.es., Babb-de-Villiers C; PHG Foundation, University of Cambridge, Cambridge, UK., Petrova D; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Instituto de Investigación Biosanitaria Ibs. GRANADA, Granada, Spain.; Escuela Andaluza de Salud Pública (EASP), Granada, Spain., Barahona-López C; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Diez-Echave P; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Hernández OR; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Fernández-Martínez NF; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Instituto de Investigación Biosanitaria Ibs. GRANADA, Granada, Spain.; Escuela Andaluza de Salud Pública (EASP), Granada, Spain., Turner H; PHG Foundation, University of Cambridge, Cambridge, UK., García-Ovejero E; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain., Craciun O; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain., Fernández-Navarro P; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Fernández-Larrea N; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., García-Esquinas E; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Kuhn I; Cambridge University Medical Library, Cambridge, UK., Jiménez-Planet V; National Library of Health Sciences, Instituto de Salud Carlos III, Madrid, Spain., Moreno V; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.; Colorectal Cancer Group, ONCOBELL Program, Institut de Recerca Biomedica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain., Rodríguez-Artalejo F; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid, Madrid, Spain.; IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain., Sánchez MJ; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Instituto de Investigación Biosanitaria Ibs. GRANADA, Granada, Spain.; Escuela Andaluza de Salud Pública (EASP), Granada, Spain., Pollan-Santamaria M; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain., Blackburn L; PHG Foundation, University of Cambridge, Cambridge, UK., Kroese M; PHG Foundation, University of Cambridge, Cambridge, UK., Pérez-Gómez B; Department of Epidemiology of Chronic Diseases, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Jazyk: angličtina
Zdroj: Systematic reviews [Syst Rev] 2024 Jun 01; Vol. 13 (1), pp. 147. Date of Electronic Publication: 2024 Jun 01.
DOI: 10.1186/s13643-024-02554-9
Abstrakt: Introduction: Personalised prevention aims to delay or avoid disease occurrence, progression, and recurrence of disease through the adoption of targeted interventions that consider the individual biological, including genetic data, environmental and behavioural characteristics, as well as the socio-cultural context. This protocol summarises the main features of a rapid scoping review to show the research landscape on biomarkers or a combination of biomarkers that may help to better identify subgroups of individuals with different risks of developing specific diseases in which specific preventive strategies could have an impact on clinical outcomes. This review is part of the "Personalised Prevention Roadmap for the future HEalThcare" (PROPHET) project, which seeks to highlight the gaps in current personalised preventive approaches, in order to develop a Strategic Research and Innovation Agenda for the European Union.
Objective: To systematically map and review the evidence of biomarkers that are available or under development in cancer, cardiovascular and neurodegenerative diseases that are or can be used for personalised prevention in the general population, in clinical or public health settings.
Methods: Three rapid scoping reviews are being conducted in parallel (February-June 2023), based on a common framework with some adjustments to suit each specific condition (cancer, cardiovascular or neurodegenerative diseases). Medline and Embase will be searched to identify publications between 2020 and 2023. To shorten the time frames, 10% of the papers will undergo screening by two reviewers and only English-language papers will be considered. The following information will be extracted by two reviewers from all the publications selected for inclusion: source type, citation details, country, inclusion/exclusion criteria (population, concept, context, type of evidence source), study methods, and key findings relevant to the review question/s. The selection criteria and the extraction sheet will be pre-tested. Relevant biomarkers for risk prediction and stratification will be recorded. Results will be presented graphically using an evidence map.
Inclusion Criteria: Population: general adult populations or adults from specific pre-defined high-risk subgroups; concept: all studies focusing on molecular, cellular, physiological, or imaging biomarkers used for individualised primary or secondary prevention of the diseases of interest; context: clinical or public health settings.
Systematic Review Registration: https://doi.org/10.17605/OSF.IO/7JRWD (OSF registration DOI).
(© 2024. The Author(s).)
Databáze: MEDLINE
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