Well-ordered Au@Ag NBPs/SiO 2 nanoarray for sensitive detection of chloramphenicol via DNAzyme-assisted SERS sensing.

Autor: Yang J; Xihua University, Chengdu 610039, PR China., Zhang R; Xihua University, Chengdu 610039, PR China., Liu J; Xihua University, Chengdu 610039, PR China., Xiong R; Xihua University, Chengdu 610039, PR China., He Y; Xihua University, Chengdu 610039, PR China. Electronic address: heyi04191@163.com., Luo X; Xihua University, Chengdu 610039, PR China., Yang X; Xihua University, Chengdu 610039, PR China.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Oct 01; Vol. 454, pp. 139806. Date of Electronic Publication: 2024 May 24.
DOI: 10.1016/j.foodchem.2024.139806
Abstrakt: Misuse of chloramphenicol (CAP) can lead to severe food safety issues. Therefore, the accurate and sensitive detection of CAP residues is important for public health. Herein, a convenient and reliable interfacial self-assembly technique was used to form a uniform Au@Ag nanobipyramids (NBPs) film on an ordered SiO 2 nanosphere array (SiO 2 NS), which served as a Raman-enhanced substrate. In conjunction with a deoxyribonucleic acid enzyme-induced signal amplification strategy, we developed a novel surface-enhanced Raman scattering (SERS) biosensor for the selective and sensitive detection of CAP. The biosensor exhibited a detection limit of 6.42 × 10 -13  mol·L -1 and a detection range of 1.0 × 10 -12 -1.0 × 10 -6  mol·L -1 . The biosensor could detect CAP in spiked milk samples with a high accuracy, and its recovery rates ranged from 97.88% to 107.86%. The as-developed biosensor with the advantages of high sensitivity and high selectivity offers a new strategy for the rapid, reliable and sensitive detection of CAP, rendering it applicable to food safety control.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Neither the entire manuscript nor any part of its content has been published or has been accepted elsewhere and this manuscript has not been submitted to any other journal. No portion of the text has been copied from other material in the literature. All of the authors in this manuscript have read and approved the final version submitted, and there are no conflicts involved in this submission.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: