18 F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 68 Ga-prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography Imaging in the Evaluation of Rare Entity Adult Embryonal Rhabdomyosarcoma of Prostate.
| Autor: | Gondhane AI; Department of Nuclear Medicine, Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India., Verma P; Department of Nuclear Medicine, Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.; Homi Bhabha National Institute, Mumbai, Maharashtra, India., Paul A; Department of Nuclear Medicine, Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India. |
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| Jazyk: | angličtina |
| Zdroj: | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India [Indian J Nucl Med] 2024 Jan-Feb; Vol. 39 (1), pp. 66-68. Date of Electronic Publication: 2024 Mar 27. |
| DOI: | 10.4103/ijnm.ijnm_110_23 |
| Abstrakt: | A 21-year-old male with embryonal rhabdomyosarcoma of the prostate was referred for 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) and 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT for initial disease staging. The PET scans revealed hypermetabolic and PSMA expressing lobulated mass involving both lobes of the prostate and weakly metabolic and PSMA expressing few bilateral pararectal and external iliac nodes, multiple bilateral lung nodules scattered over the lung parenchyma and multiple bone marrow lesions in both axial and appendicular skeleton. Magnetic resonance imaging prostate showed gross prostatomegaly with large lobulated T2 hyperintense heterogeneously enhancing mass lesion showing restricted diffusion, involving both lobes of the prostate with extraprostatic spread along anterior, posterior, and left lateral margins with evidence of lymph nodal and osseous metastases. The demonstration of increased uptake of 18 F-FDG and 68 Ga-PSMA in the primary as well as bilateral pararectal and external iliac nodes, multiple bilateral lung nodules, and multiple bone marrow lesions in both axial and appendicular skeleton indicates a potential role of 18 F-FDG PET/CT and 68 Ga-PSMA PET/CT in disease staging in this rare aggressive tumor of the prostate. Competing Interests: There are no conflicts of interest. (Copyright: © 2024 Indian Journal of Nuclear Medicine.) |
| Databáze: | MEDLINE |
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