Chemical Constituents and Pharmacological Properties of Frankincense: Implications for Anticancer Therapy.

Autor: Wu YR; College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., Xiong W; Department of Andrology, the First Hospital of Hunan University of Chinese Medicine, Changsha, 41007, China., Dong YJ; College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., Chen X; College of Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., Zhong YY; College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., He XL; College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., Wang YJ; College of Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China., Lin QF; Department of Andrology, the First Hospital of Hunan University of Chinese Medicine, Changsha, 41007, China., Tian XF; College of Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China.; Hunan Provincial Key Laboratory of Traditional Chinese Medicine Prescription and Transformation, Changsha, 410208, China., Zhou Q; Department of Andrology, the First Hospital of Hunan University of Chinese Medicine, Changsha, 41007, China. 310094@hnucm.edu.cn.; Hunan Sexual and Reproductive Health Clinical Medical Research Center of Traditional Chinese Medicine, Changsha, 410021, China. 310094@hnucm.edu.cn.
Jazyk: angličtina
Zdroj: Chinese journal of integrative medicine [Chin J Integr Med] 2024 Aug; Vol. 30 (8), pp. 759-767. Date of Electronic Publication: 2024 May 31.
DOI: 10.1007/s11655-024-4105-x
Abstrakt: The discovery of novel antitumor agents derived from natural plants is a principal objective of anticancer drug research. Frankincense, a widely recognized natural antitumor medicine, has undergone a systematic review encompassing its species, chemical constituents, and diverse pharmacological activities and mechanisms. The different species of frankincense include Boswellia serrata, Somali frankincense, Boswellia frereana, and Boswellia arabica. Various frankincense extracts and compounds exhibit antitumor, anti-inflammatory, and hepatoprotective properties and antioxidation, memory enhancement, and immunological regulation capabilities. They also have comprehensive effects on regulating flora. Frankincense and its principal chemical constituents have demonstrated promising chemoprophylactic and therapeutic abilities against tumors. This review provides a systematic summary of the mechanism of action underlying the antitumor effects of frankincense and its major constituents, thus laying the foundations for developing effective tumor-combating targets.
(© 2024. The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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