Examining the relationship between land use and childhood leukemia and lymphoma in Tehran.

Autor: Norzaee S; Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran.; Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran., Yunesian M; Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.; Center for Air Pollution Research, Institute of Environmental Research, Tehran University of Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran., Ghorbanian A; Department of Photogrammetry and Remote Sensing, Faculty of Geodesy and Geomatics Engineering, K. N. Toosi University of Technology, Tehran, Iran., Farzadkia M; Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran.; Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran., Rezaei Kalantary R; Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran.; Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran., Kermani M; Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran. kermani.m@iums.ac.ir.; Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. kermani.m@iums.ac.ir., Nourbakhsh SM; Department of Pediatrics, Pediatric Hematology and Oncology Section, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran., Eghbali A; Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 May 30; Vol. 14 (1), pp. 12417. Date of Electronic Publication: 2024 May 30.
DOI: 10.1038/s41598-024-63309-z
Abstrakt: We conducted a hospital-based case-control study to explore the association between proximity to various land use types and childhood leukemia and lymphoma. This research involved 428 cases of childhood leukemia and lymphoma (2016-2021), along with a control group of 428 children aged 1-15 in Tehran. We analyzed the risk of childhood cancer associated with land use by employing logistic regression adjusted for confounding factors such as parental smoking and family history. The odds ratio (OR) for children with leukemia and lymphoma residing within 100 m of the nearest highway was 1.87 (95% CI = 1.00-3.49) and 1.71 (95% CI = 1.00-2.93), respectively, in comparison to those living at a distance of 1000 m or more from a highway. The OR for leukemia with exposure to petrol stations within 100 m was 2.15 (95% CI = 1.00-4.63), and for lymphoma it was 1.09 (95% CI = 0.47-2.50). A significant association was observed near power lines (OR = 3.05; 95% CI = 0.97-9.55) within < 100 m for leukemia. However, no significant association was observed between power lines and the incidence of childhood lymphoma. There was no association between bus stations, major road class 2, and the incidence of childhood leukemia and lymphoma. In conclusion, our results suggest a possible association between the incidence of childhood leukemia and proximity to different urban land uses (i.e., highways and petrol stations). This study is the first step in understanding how urban land use affects childhood leukemia and lymphoma in Tehran. However, comprehensive studies considering individual-level data and specific pollutants are essential for a more nuanced understanding of these associations.
(© 2024. The Author(s).)
Databáze: MEDLINE
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