Naked mole-rats: at the heart of it.

Autor: Gabillard-Lefort C; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France., Mialet-Perez J; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France., Lenaers G; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France., Baris OR; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France. Electronic address: olivier.baris@univ-angers.fr.
Jazyk: angličtina
Zdroj: Trends in molecular medicine [Trends Mol Med] 2024 Oct; Vol. 30 (10), pp. 906-907. Date of Electronic Publication: 2024 May 29.
DOI: 10.1016/j.molmed.2024.05.008
Abstrakt: Faulkes et al. recently showed that naked mole-rats (NMRs) have a very distinctive cardiac gene expression profile among other African mole-rats, as well as metabolic variations that result from their chronic exposure to a hypoxic environment. These adaptations might underlie their resistance to cardiac ischemic injuries.
Competing Interests: Declaration of Interests The authors have no interests to declare.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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