Mobile Phone-Based Confidential Social Network Referrals for HIV Testing (CONSORT): Protocol for a Randomized Controlled Trial.

Autor:	Ostermann J; Department of Health Services Policy & Management, University of South Carolina, Columbia, SC, United States., Njau B; Kilimanjaro Christian Medical University College, Moshi, United Republic of Tanzania., van Zwetselaar M; Zwets IT, Harskamp, Netherlands., Yamanis T; School of International Service, American University, Washington, DC, United States., McClimans L; Department of Philosophy, University of South Carolina, Columbia, SC, United States., Mwangi R; Kilimanjaro Christian Medical University College, Moshi, United Republic of Tanzania., Beti M; Kilimanjaro Clinical Research Institute, Moshi, United Republic of Tanzania., Hobbie A; Center for Health Policy and Inequalities Research, Duke University, Durham, SC, United States., Gass SJ; Department of Health Services Policy & Management, University of South Carolina, Columbia, SC, United States., Mtuy T; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom., Thielman N; Department of Medicine, Duke University School of Medicine, Durham, NC, United States.
Jazyk:	angličtina
Zdroj:	JMIR research protocols [JMIR Res Protoc] 2024 May 30; Vol. 13, pp. e55068. Date of Electronic Publication: 2024 May 30.
DOI:	10.2196/55068
Abstrakt:	Background: Critical to efforts to end the HIV epidemic is the identification of persons living with HIV who have yet to be diagnosed and engaged in care. Expanded HIV testing outreach efforts need to be both efficient and ambitious, targeting the social networks of persons living with HIV and those at above-average risk of undiagnosed HIV infection. The ubiquity of mobile phones across many high HIV prevalence settings has created opportunities to leverage mobile health (mHealth) technologies to engage social networks for HIV testing outreach, prevention, and treatment. Objective: The purpose of this study is to evaluate the acceptability and efficacy of a novel mHealth intervention, "Confidential Social Network Referrals for HIV Testing (CONSORT)," to nudge at-risk individuals to test for HIV using SMS text messages. Methods: We will conduct the CONSORT study in Moshi, Tanzania, the commercial center and administrative capital of the Kilimanjaro Region in northern Tanzania. After qualitative formative work and pilot testing, we will enroll 400 clients presenting for HIV counseling and testing and 200 persons living with HIV and receiving care at HIV care and treatment centers as "inviters" into a randomized controlled trial. Eligible participants will be aged 18 years or older and live, work, or regularly receive care in Moshi. We will randomize inviters into 1 of 2 study arms. All inviters will be asked to complete a survey of their HIV testing and risk behaviors and to think of social network contacts who would benefit from HIV testing. They will then be asked to whom they would prefer to extend an HIV testing invitation in the form of a physical invitation card. Arm 1 participants will also be given the opportunity to extend CONSORT invitations in the form of automated confidential SMS text messages to any of their social network contacts or "invitees." Arm 2 participants will be offered physical invitation cards alone. The primary outcome will be counselor-documented uptake of HIV testing by invitees within 30 days of inviter enrollment. Secondary outcomes will include the acceptability of CONSORT among inviters, the number of new HIV diagnoses, and the HIV risk of invitees who present for testing. Results: Enrollment in the randomized controlled trial is expected to start in September 2024. The findings will be disseminated to stakeholders and published in peer-reviewed journals. Conclusions: If CONSORT is acceptable and effective for increasing the uptake of HIV testing, given the minimal costs of SMS text reminders and the potential for exponential but targeted growth using chain referrals, it may shift current practices for HIV testing programs in the area. Trial Registration: ClincalTrials.gov NCT05967208; https://clinicaltrials.gov/study/NCT05967208. International Registered Report Identifier (irrid): PRR1-10.2196/55068. (©Jan Ostermann, Bernard Njau, Marco van Zwetselaar, Thespina Yamanis, Leah McClimans, Rose Mwangi, Melkiory Beti, Amy Hobbie, Salomé-Joelle Gass, Tara Mtuy, Nathan Thielman. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 30.05.2024.)
Databáze:	MEDLINE
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