Nanotechnology: The Future for Diagnostic and Therapeutic Intervention in Cardiovascular Diseases is Here.

Autor:	Elsaygh J; From the Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY., Zaher A; From the Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY., Parikh MA; From the Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY.; Weill Department of Medicine, Weill Cornell Medicine, New York, NY., Frishman WH; Department of Medicine, New York Medical College, Valhalla, NY., Peterson SJ; From the Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY.; Weill Department of Medicine, Weill Cornell Medicine, New York, NY.
Jazyk:	angličtina
Zdroj:	Cardiology in review [Cardiol Rev] 2024 May 30. Date of Electronic Publication: 2024 May 30.
DOI:	10.1097/CRD.0000000000000727
Abstrakt:	With advances in technology and medicine over the last 3 decades, cardiovascular medicine has evolved tremendously. Nanotechnology provides a promising future in personalized precision medicine. In this review, we delve into the current and prospective applications of nanotechnology and nanoparticles in cardiology. Nanotechnology has allowed for point-of-care testing such as high-sensitivity troponins, as well as more precise cardiac imaging. This review is focused on 3 diseases within cardiology: coronary artery disease, heart failure, and valvular heart disease. The use of nanoparticles in coronary stents has shown success in preventing in-stent thrombosis, as well as using nanosized drug delivery medications to prevent neointimal proliferation in a way that spares systemic toxicity. In addition, by using nanoparticles as drug delivery systems, nanotechnology can be utilized in the delivery of goal-directed medical therapy in heart failure patients. It has also been shown to improve cell therapy in this patient population by helping in cell retention of grafts. Finally, the use of nanoparticles in the manufacturing of bioprosthetic valves provides a promising future for the longevity and success of cardiac valve repair and replacement. Competing Interests: Disclosure: The authors declare no conflict of interest. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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