Effects of mindfulness-based cognitive therapy for Chinese adults with PTSD symptoms: protocol for a randomised controlled trial.

Autor: Mak BSW; Faculty of Education, The Chinese University of Hong Kong, Hong Kong, China., Zhang D; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China., Powell CLYM; Mind HK, Hong Kong, China., Leung MKW; Department of Family Medicine & Primary Health Care, New Territories East Cluster, Hospital Authority, Hong Kong, China., Lo HHM; Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hong Kong, China., Yang X; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China., Yip BHK; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China., Lee EKP; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China., Xu Z; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China., Wong SYS; JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China. yeungshanwong@cuhk.edu.hk.
Jazyk: angličtina
Zdroj: BMC psychiatry [BMC Psychiatry] 2024 May 29; Vol. 24 (1), pp. 400. Date of Electronic Publication: 2024 May 29.
DOI: 10.1186/s12888-024-05840-x
Abstrakt: Introduction: Emerging evidence supports mindfulness as a potential psychotherapy for post-traumatic stress disorder (PTSD). Individuals with subthreshold PTSD experience significant impairment in their daily life and functioning due to PTSD symptoms, despite not meeting the full diagnostic criteria for PTSD in DSM-5. Mindfulness skills, including non-judgmental acceptance, attentional control and openness to experiences may help alleviate PTSD symptoms by targeting characteristics such as intensified memory processing, dysregulated hyperarousal, avoidance, and thought suppression. This trial aims to test the effects of mindfulness-based cognitive therapy (MBCT) when compared to an active control.
Method and Analysis: This 1:1 randomised controlled trial will enroll 160 participants with PTSD symptoms in 2 arms (MBCT vs. Seeking Safety), with both interventions consisting of 8 weekly sessions lasting 2 h each week and led by certified instructors. Assessments will be conducted at baseline (T0), post-intervention (T1), and 3 months post-intervention (T2), with the primary outcome being PTSD symptoms measured by the PTSD checklist for DSM-5 (PCL-5) at T1. Secondary outcomes include depression, anxiety, attention, experimental avoidance, rumination, mindfulness, and coping skills. Both intention-to-treat and per-protocol analyses will be performed. Mediation analysis will investigate whether attention, experimental avoidance, and rumination mediate the effect of mindfulness on PTSD symptoms.
Discussion: The proposed study will assess the effectiveness of MBCT in improving PTSD symptoms. The findings are anticipated to have implications for various areas of healthcare and contribute to the enhancement of existing intervention guidelines for PTSD.
Trial Registration Number: ChiCTR2200061863.
(© 2024. The Author(s).)
Databáze: MEDLINE
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