Lung function and quality of life one year after severe COVID-19 in Brazil.

Autor:	Prata TA; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Leite AS; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Augusto VM; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Bretas DC; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Andrade BH; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Oliveira JDGF; Hospital Eduardo de Menezes - Fundação Hospitalar de Minas Gerais - FHEMIG - Belo Horizonte (MG) Brasil., Batista AP; Universidade Federal de Ouro Preto - UFOP - Ouro Preto (MG) Brasil., Machado-Coelho GLL; Universidade Federal de Ouro Preto - UFOP - Ouro Preto (MG) Brasil., Mancuzo E; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil., Marinho CC; Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG) Brasil.
Jazyk:	angličtina
Zdroj:	Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia [J Bras Pneumol] 2024 May 27; Vol. 50 (2), pp. e20230261. Date of Electronic Publication: 2024 May 27 (Print Publication: 2024).
DOI:	10.36416/1806-3756/e20230261
Abstrakt:	Objective: To evaluate symptoms, lung function, and quality of life of a cohort of patients hospitalized for severe COVID-19 12 months after hospital admission. Methods: This was a cross-sectional study. We included severe COVID-19 survivors hospitalized in one of three tertiary referral hospitals for COVID-19 in the city of Belo Horizonte, Brazil. Participants were submitted to lung function and six-minute walk tests and completed the EQ-5D-3L questionnaire. Results: The whole sample comprised 189 COVID-19 survivors (mean age = 59.6 ± 13.4 years) who had been admitted to a ward only (n = 96; 50.8%) or to an ICU (n = 93; 49.2%). At 12 months of follow-up, 43% of patients presented with dyspnea, 27% of whom had a restrictive ventilatory disorder and 18% of whom presented with impaired DLCO. There were no significant differences in FVC, FEV1, and TLC between the survivors with or without dyspnea. However, those who still had dyspnea had significantly more impaired DLCO (14.9% vs. 22.4%; p < 0.020) and poorer quality of life. Conclusions: After one year, survivors of severe COVID-19 in a middle-income country still present with high symptom burden, restrictive ventilatory changes, and loss of quality of life. Ongoing follow-up is needed to characterize long COVID-19 and identify strategies to mitigate its consequences.
Databáze:	MEDLINE
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