Seizures and severe methaemoglobinaemia following accidental ingestion of amyl nitrite.

Autor: Timmons P; Infectious Disease/Internal Medicine, Queen Elizabeth University Hospital, Glasgow, UK patrick.timmons2@nhs.scot.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2024 May 28; Vol. 17 (5). Date of Electronic Publication: 2024 May 28.
DOI: 10.1136/bcr-2023-259384
Abstrakt: We present a case of a man in his late 40s presenting with generalised tonic-clonic seizures and profound methaemoglobinaemia shortly after inadvertent ingestion of amyl nitrite. Arterial blood gas analysis demonstrated methaemoglobin levels exceeding the upper detection threshold of our analyser, accompanied with profound cyanosis despite apparent oxygen saturations of 94%. Prompt administration of intravenous methylene blue led to a rapid and complete recovery. This case highlights the importance of swift recognition and treatment of methaemoglobinaemia particularly when the precipitating factor may be unknown at the time of presentation. This case also demonstrates the potential limitations of bedside blood gas analysers in diagnosis.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE