Anterior segment swept-source optical coherence tomography and ultrasound biomicroscopy in iris and ciliary body lesions.

Autor: Mirzayev I; Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.; Halil Şıvgın Çubuk State Hospital, Ophthalmology Clinic, Ankara, Turkey., Gündüz AK; Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.; Private Eye Clinic, Ankara, Turkey., Gündüz ÖÖ; Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey., Özalp Ateş FS; Department of Biostatistics and Medical Informatics, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey., Okcu Heper A; Department of Pathology, Ankara University Faculty of Medicine, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Expert review of medical devices [Expert Rev Med Devices] 2024 May; Vol. 21 (5), pp. 439-446. Date of Electronic Publication: 2024 May 27.
DOI: 10.1080/17434440.2024.2344668
Abstrakt: Objectives: Differentiation of iris and ciliary body lesions as benign or malignant and cystic or solid is important. The aim of this study was to compare anterior segment swept-source optical coherence tomography (AS SS-OCT) and ultrasound biomicroscopy (UBM) findings in iris and ciliary body tumors.
Research Design and Methods: Forty-two eyes of 38 cases with iris and ciliary body tumors imaged with UBM and AS SS-OCT between September 2018 and September 2023 were evaluated retrospectively.
Results: Of 42 eyes, 14 had melanoma, 14 iris pigment epithelial (IPE) cysts, 7 nevi, 3 Lisch nodules, 2 iris stromal cysts, 1 pars plana cysts, and 1 iris mammillations. An equivalent (100%) visualization of the anterior tumor margin was obtained with both techniques. Compared to AS SS-OCT, UBM was superior for posterior margin visualization in melanocytic tumors and IPE cysts. Bland-Altman plots demonstrated good agreement between UBM and AS SS-OCT for melanocytic tumors < 2.5 mm in base diameter and < 2 mm in thickness.
Conclusions: Although, UBM is the gold standard for ciliary body and iridociliary tumors. AS SS-OCT should be considered as an excellent alternative to UBM, especially in minimally elevated iris lesions.
Databáze: MEDLINE