Venous Thromboembolism Risk and Adherence to Pharmacological Thromboprophylaxis in Hospitalized Patients in Uruguay: First Nationwide Study.

Autor:	Mérola V; Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay., Pizzarossa AC; Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay., López M; CASMU, Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay., Peverelli F; MUCAM, Hospital Maciel, Montevideo, Uruguay., Bruno G; Hospital Maciel, Montevideo, Uruguay., González M; Hospital Pasteur, Montevideo, Uruguay., Roca F; Asociación Española de Socorros Mutuos, Hospital Pasteur, Montevideo, Uruguay., Dentone L; Hospital Policial, Montevideo, Uruguay., Pérez G; Hospital Británico, Montevideo, Uruguay., Da Silveira L; COMECA, Canelones, Uruguay., Díaz L; SMI, MUCAM, Montevideo, Uruguay., Tafuri J; COMERO, Rocha, Uruguay., Cuadro R; Sanatorio Americano, Montevideo, Uruguay., Zaquiere M; Círculo Católico, Montevideo, Uruguay., Bartaburu G; Hospital Departamental de Rivera, Rivera, Uruguay., Pacello F; Hospital Departamental de Rivera, Rivera, Uruguay., Celio C; Asistencial Médica, Maldonado, Uruguay., López MJ; CAMEDUR, Durazno, Uruguay., Viana M; INCA, Hospital de Canelones, Montevideo y Canelones, Uruguay., Fraga L; COSEM, Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay., Blanco V; CAAMEPA, Canelones, Uruguay., Chalart P; Hospital de Artigas, GREMEDA, Artigas, Uruguay., Leal D; AMEDRIN, Río Negro, Uruguay., Rodríguez X; Hospital de Cerro Largo, Cerro Largo, Uruguay., Teti L; Hospital de Rocha, Rocha, Uruguay., Goñi C; COMEFLO, Flores, Uruguay., Infante E; Hospital de Flores, Flores, Uruguay., Prícoli A; Hospital de Fray Bentos, Río Negro, Uruguay., Altieri V; CAMS, Soriano, Uruguay., Guillermo C; Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay., Martínez R; Hospital de Clínicas 'Dr Manuel Quintela', Montevideo, Uruguay.
Jazyk:	angličtina
Zdroj:	Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2024 Jan-Dec; Vol. 30, pp. 10760296241256368.
DOI:	10.1177/10760296241256368
Abstrakt:	Introduction: Venous thromboembolism (VTE) is a serious, frequent, and preventable medical complication in hospitalized patients. Although the efficacy of prophylaxis (pharmacological and/or mechanical) has been demonstrated, compliance with prophylaxis is poor at international and national levels. Aim: To determine the indication and use of pharmacological thromboprophylaxis in hospitalized patients in Uruguay. Methods: An observational, descriptive, cross-sectional, multicentre study involving 31 nationwide healthcare facilities was conducted. Baseline characteristics associated with hospital admission, the percentage of the population with an indication for thromboprophylaxis, and the percentage of patients receiving pharmacological thromboprophylaxis were assessed. The VTE risk was determined using the Padua score for medical patients; the Caprini score for surgical patients; the Royal College of Obstetricians and Gynaecologists (RCOG) guidelines for pregnant-postpartum patients. Results: 1925 patients were included, representing 26% of hospitalized patients in Uruguay. 71.9% of all patients were at risk of VTE. Of all patients at risk of VTE, 58.6% received pharmacological thromboprophylaxis. The reasons for not receiving thromboprophylaxis were prescribing omissions in 16.1% of cases, contraindication in 15.9% and 9.4% of patients were already anticoagulated for other reasons. Overall, just 68% of patients were "protected" against VTE. Recommendations of major thromboprophylaxis guidelines were followed in 70.1% of patients at risk. Conclusions: Despite the progress made in adherence to thromboprophylaxis indications, nonadherence remains a problem, affecting one in six patients at risk of VTE in Uruguay. Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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