Comparative transcriptome analysis of Fusarium graminearum challenged with distinct fungicides and functional analysis of FgICL gene.

Autor: Guo X; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., He K; National Animal Protozoa Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China., Li M; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., Zhang Y; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., Jiang J; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., Qian L; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., Gao X; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China., Zhang C; College of Plant Protection, Anhui Agricultural University, Hefei 230036, China., Liu S; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China; Henan Engineering Technology Research Center of Green Plant Protection, Luoyang 471023, China. Electronic address: liushengmingzb@163.com.
Jazyk: angličtina
Zdroj: Genomics [Genomics] 2024 Jul; Vol. 116 (4), pp. 110869. Date of Electronic Publication: 2024 May 24.
DOI: 10.1016/j.ygeno.2024.110869
Abstrakt: Fusarium graminearum is an economically important phytopathogenic fungus. Chemical control remains the dominant approach to managing this plant pathogen. In the present study, we performed a comparative transcriptome analysis to understand the effects of four commercially used fungicides on F. graminearum. The results revealed a significant number of differentially expressed genes related to carbohydrate, amino acid, and lipid metabolism, particularly in the carbendazim and phenamacril groups. Central carbon pathways, including the TCA and glyoxylate cycles, were found to play crucial roles across all treatments except tebuconazole. Weighted gene co-expression network analysis reinforced the pivotal role of central carbon pathways based on identified hub genes. Additionally, critical candidates associated with ATP-binding cassette transporters, heat shock proteins, and chitin synthases were identified. The crucial functions of the isocitrate lyase in F. graminearum were also validated. Overall, the study provided comprehensive insights into the mechanisms of how F. graminearum responds to fungicide stress.
Competing Interests: Declaration of competing interest The authors declare that they have no competing interests.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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