Ingenious fluorescent probes for biogenic amine and their applications in bioimaging and food spoilage detection.

Autor: Wang A; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China., Tang F; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China., Zang T; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China., Liu X; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China., Cheng G; College of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255000, China., Chen W; College of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255000, China., Shu W; School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China., Li D; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China., Tang Y; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding 071002, China. Electronic address: tangyh86@163.com., Sun X; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China. Electronic address: xiaofengsun@sdut.edu.cn., Xiao H; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China. Electronic address: haibinxiao@sdut.edu.cn.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Oct 01; Vol. 454, pp. 139714. Date of Electronic Publication: 2024 May 22.
DOI: 10.1016/j.foodchem.2024.139714
Abstrakt: Food safety issues have received much attention. Biogenic amines are considered important markers of food spoilage. Accurate detection of biogenic amines is important for food quality monitoring. Herein, we developed two coumarin-difluoroboron β-diketonate hybrid probes, 1 and 2, for detection of amines. Both probes possess large conjugated structures and donor-acceptor-donor configuration, exhibiting solvatochromic effects due to intramolecular charge transfer mechanism. Upon reaction with amines, the boron atom in difluoroboron unit can interact with lone pair electrons of nitrogen atom, thus resulting in significant changes in absorption and fluorescence properties. These probes were successfully utilized to image amine in live cells and liver tissues. Moreover, by photographing probe-loaded food extract supernatant, we establish the relationship between color parameters and food storage time, which can easily indicate food spoilage process. This work and its findings hold promise for providing potential strategies for real-time and convenient detection of food freshness.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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