Development of a NiFe 2 O 4 covalent organic framework based magnetic solid-phase extraction approach for specific capture of quinolones in animal innards prior to UHPLC-Q-Orbitrap HRMS detection.

Autor: Lin S; Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding 071002, PR China; Analysis and Testing Center, Inner Mongolia University of Science and Technology, Baotou 014010, PR China., Lv YK; Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding 071002, PR China; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Baoding 071002, PR China., Zhu A; Large Scale Instruments Shared Service Platform, Hebei University, Baoding 071002, PR China., Su M; Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding 071002, PR China; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Baoding 071002, PR China., Li X; School of Public Health, Hebei University, Baoding 071002, China., Liang SX; Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Materials Science, Hebei University, Baoding 071002, PR China; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Baoding 071002, PR China. Electronic address: liangsx168@126.com.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Oct 01; Vol. 454, pp. 139796. Date of Electronic Publication: 2024 May 22.
DOI: 10.1016/j.foodchem.2024.139796
Abstrakt: This study aimed to present a selective and effective method for analyzing quinolones (QNs) in food matrix. Herein, a NiFe 2 O 4 -based magnetic sodium disulfonate covalent organic framework (NiFe 2 O 4 /COF) was prepared using a simple solvent-free grinding method, and was adopted as a selective adsorbent for magnetic solid phase extraction of QNs. Coupled with UHPLC-Q-Orbitrap HRMS, an efficient method for simultaneous detection of 18 kinds of QNs was established. The method exhibited good linearity (0.01-100 ng g -1 ), high sensitivity (LODs ranging from 0.0011 to 0.0652 ng g -1 ) and precision (RSDs below 9.5%). Successful extraction of QNs from liver and kidney samples was achieved with satisfactory recoveries ranging from 82.2% to 108.4%. The abundant sulfonate functional groups on NiFe 2 O 4 /COF facilitated strong affinity to QNs through electrostatic and hydrogen bonding interactions. The proposed method provides a new idea for the extraction of contaminants with target selectivity.
Competing Interests: Declaration of competing interest The authors declare that none of the work presented in this study may have been impacted by any known competing financial interests or personal ties.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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