| Autor: |
Sandhu ZA; Department of Chemistry, Faculty of Science, Hafiz Hayat Campus, University of Gujrat, Gujrat 50700, Pakistan., Raza MA; Department of Chemistry, Faculty of Science, Hafiz Hayat Campus, University of Gujrat, Gujrat 50700, Pakistan., Alqurashi A; Department of Biology, College of Science, Taibah University, Madinah 42353, Saudi Arabia., Sajid S; Department of Chemistry, Faculty of Science, University of Engineering and Technology, Lahore 54890, Pakistan., Ashraf S; Department of Chemistry, Faculty of Science, Hafiz Hayat Campus, University of Gujrat, Gujrat 50700, Pakistan., Imtiaz K; Department of Chemistry, Faculty of Science, Hafiz Hayat Campus, University of Gujrat, Gujrat 50700, Pakistan., Aman F; Department of Chemistry, The University of Lahore, Sargodha Campus, Sargodha 40100, Pakistan., Alessa AH; Department of Biology, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia., Shamsi MB; Centre for Genetics and Inherited Diseases (CGID), Taibah University, Madinah 42353, Saudi Arabia.; Department Basic Medical Sciences, College of Medicine, Taibah University, Madinah 42353, Saudi Arabia., Latif M; Centre for Genetics and Inherited Diseases (CGID), Taibah University, Madinah 42353, Saudi Arabia.; Department Basic Medical Sciences, College of Medicine, Taibah University, Madinah 42353, Saudi Arabia. |
| Abstrakt: |
In recent years, nanotechnology has achieved a remarkable status in shaping the future of biological applications, especially in combating fungal diseases. Owing to excellence in nanotechnology, iron nanoparticles (Fe NPs) have gained enormous attention in recent years. In this review, we have provided a comprehensive overview of Fe NPs covering key synthesis approaches and underlying working principles, the factors that influence their properties, essential characterization techniques, and the optimization of their antifungal potential. In addition, the diverse kinds of Fe NP delivery platforms that command highly effective release, with fewer toxic effects on patients, are of great significance in the medical field. The issues of biocompatibility, toxicity profiles, and applications of optimized Fe NPs in the field of biomedicine have also been described because these are the most significant factors determining their inclusion in clinical use. Besides this, the difficulties and regulations that exist in the transition from laboratory to experimental clinical studies (toxicity, specific standards, and safety concerns) of Fe NPs-based antifungal agents have been also summarized. |
