Salvianolic acid A alleviates H 2 O 2 -induced endothelial oxidative injury via miR-204-5p.
Autor: | Qiao X; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Cao S; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Chen S; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Guo Y; Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Chen N; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zheng Y; The 903rd Hospital of the People's Liberation Army, Hangzhou, Zhejiang, China. zhengying72@163.com., Jin B; School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. jinbo@zcmu.edu.cn. |
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Jazyk: | angličtina |
Zdroj: | Scientific reports [Sci Rep] 2024 May 24; Vol. 14 (1), pp. 11931. Date of Electronic Publication: 2024 May 24. |
DOI: | 10.1038/s41598-024-62556-4 |
Abstrakt: | Oxidative stress induced endothelial dysfunction plays a particularly important role in promoting the development of cardiovascular diseases (CVDs). Salvianolic acid A (SalA) is a water-soluble component of traditional Chinese medicine Salvia miltiorrhiza Bunge with anti-oxidant potency. This study aims to explore the regulatory effect of SalA on oxidative injury using an in vitro model of H (© 2024. The Author(s).) |
Databáze: | MEDLINE |
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